Recombinant multi-species BAP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BAP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]
The Alternative Names of target: 2300006C11Rik,BAP1,BRCA1-associated protein 1,Bap1,Cerebral protein 6,HUCEP-13,KURIS,TPDS1,UBM2,UCHL2,UVM2,Ubiquitin carboxyl-terminal hydrolase BAP1,hucep-6,mKIAA0272,uch-x4

Target products collectionGo to BAP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T92628-Ag-1/ GM-Tg-hg-T92628-Ag-2 Human BAP1 protein Human
GM-Tg-rg-T92628-Ag-1/ GM-Tg-rg-T92628-Ag-2 Rat BAP1 protein Rat
GM-Tg-mg-T92628-Ag-1/ GM-Tg-mg-T92628-Ag-2 Mouse BAP1 protein Mouse
GM-Tg-cynog-T92628-Ag-1/ GM-Tg-cynog-T92628-Ag-2 Cynomolgus/Rhesus macaque BAP1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T92628-Ag-1/ GM-Tg-felg-T92628-Ag-2 Feline BAP1 protein Feline
GM-Tg-cang-T92628-Ag-1/ GM-Tg-cang-T92628-Ag-2 Canine BAP1 protein Canine
GM-Tg-bovg-T92628-Ag-1/ GM-Tg-bovg-T92628-Ag-2 Bovine BAP1 protein Bovine
GM-Tg-equg-T92628-Ag-1/ GM-Tg-equg-T92628-Ag-2 Equine BAP1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T92628-Ag-1/ GM-Tg-hg-T92628-Ag-2; GM-Tg-rg-T92628-Ag-1/ GM-Tg-rg-T92628-Ag-2;
GM-Tg-mg-T92628-Ag-1/ GM-Tg-mg-T92628-Ag-2; GM-Tg-cynog-T92628-Ag-1/ GM-Tg-cynog-T92628-Ag-2;
GM-Tg-felg-T92628-Ag-1/ GM-Tg-felg-T92628-Ag-2; GM-Tg-cang-T92628-Ag-1/ GM-Tg-cang-T92628-Ag-2;
GM-Tg-bovg-T92628-Ag-1/ GM-Tg-bovg-T92628-Ag-2; GM-Tg-equg-T92628-Ag-1/ GM-Tg-equg-T92628-Ag-2
Products Name BAP1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name BAP1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BAP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.