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Target
sublocation: Introcelluar Protein.
This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013]
| Target ID |
GM-T92628
|
| Target Name |
BAP1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
8314
|
| Gene ID |
100051934 (Equus caballus), 100124510 (Bos taurus), 101092671 (Felis catus), 104416 (Mus musculus) 306257 (Rattus norvegicus), 484737 (Canis lupus familiaris), 697221 (Macaca mulatta), 8314 (Homo sapiens)
|
| Target Alternative Names |
2300006C11Rik,BAP1,BRCA1-associated protein 1,Bap1,Cerebral protein 6,HUCEP-13,KURIS,TPDS1,UBM2,UCHL2,UVM2,Ubiquitin carboxyl-terminal hydrolase BAP1,hucep-6,mKIAA0272,uch-x4
|
| Uniprot Accession |
A2VDM8,Q99PU7,D3ZHS6,Q92560
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000020681, ENSBTAG00000045817, ENSMUSG00000021901, ENSCAFG00845030530, ENSMMUG00000016982, ENSG00000163930
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of BAP1 cDNA Clones/ORF Plasmid
BAP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8314 | Pre-made Human BAP1/UBM2/UVM2 siRNA oligo Duplex | 8314 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo306257 | Pre-made Rat Bap1 siRNA oligo Duplex | 306257 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo104416 | Pre-made Mouse Bap1/uch-x4/mKIAA0272 siRNA oligo Duplex | 104416 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697221 | Pre-made Cynomolgus/Rhesus macaque BAP1 siRNA oligo Duplex | 697221 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092671 | Pre-made Cat/Feline BAP1 siRNA oligo Duplex | 101092671 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484737 | Pre-made Dog/Canine BAP1 siRNA oligo Duplex | 484737 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100124510 | Pre-made Bovines/Cattle BAP1 siRNA oligo Duplex | 100124510 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051934 | Pre-made Equine/Horse BAP1 siRNA oligo Duplex | 100051934 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BAP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T92628-Ab | Human | Anti-Human BAP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T92628-Ab | Rat | Anti-Rat BAP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T92628-Ab | Mouse | Anti-Mouse BAP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T92628-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BAP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T92628-Ab | Cat/Feline | Anti-Cat/Feline BAP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T92628-Ab | Dog/Canine | Anti-Dog/Canine BAP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T92628-Ab | Bovines/Cattle | Anti-Bovines/Cattle BAP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T92628-Ab | Equine/Horse | Anti-Equine/Horse BAP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
BAP1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T92628-Ag | Human | Human BAP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T92628-Ag | Rat | Rat BAP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T92628-Ag | Mouse | Mouse BAP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T92628-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BAP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T92628-Ag | Cat/Feline | Cat/Feline BAP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T92628-Ag | Dog/Canine | Dog/Canine BAP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T92628-Ag | Bovines/Cattle | Bovines/Cattle BAP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T92628-Ag | Equine/Horse | Equine/Horse BAP1 recombinant protein | Mammalian cell | Detail |