Recombinant multi-species BCAT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BCAT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010]
The Alternative Names of target: BCAT(c),BCAT1,BCATC,BCATc,BCT1,Bcat1,Bcatc,Branched-chain-amino-acid aminotransferase,ECA39,Eca39,MECA39,PNAS121,PP18,cytosolic

Target products collectionGo to BCAT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T92557-Ag-1/ GM-Tg-hg-T92557-Ag-2 Human BCAT1 protein Human
GM-Tg-rg-T92557-Ag-1/ GM-Tg-rg-T92557-Ag-2 Rat BCAT1 protein Rat
GM-Tg-mg-T92557-Ag-1/ GM-Tg-mg-T92557-Ag-2 Mouse BCAT1 protein Mouse
GM-Tg-cynog-T92557-Ag-1/ GM-Tg-cynog-T92557-Ag-2 Cynomolgus/Rhesus macaque BCAT1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T92557-Ag-1/ GM-Tg-felg-T92557-Ag-2 Feline BCAT1 protein Feline
GM-Tg-cang-T92557-Ag-1/ GM-Tg-cang-T92557-Ag-2 Canine BCAT1 protein Canine
GM-Tg-bovg-T92557-Ag-1/ GM-Tg-bovg-T92557-Ag-2 Bovine BCAT1 protein Bovine
GM-Tg-equg-T92557-Ag-1/ GM-Tg-equg-T92557-Ag-2 Equine BCAT1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T92557-Ag-1/ GM-Tg-hg-T92557-Ag-2; GM-Tg-rg-T92557-Ag-1/ GM-Tg-rg-T92557-Ag-2;
GM-Tg-mg-T92557-Ag-1/ GM-Tg-mg-T92557-Ag-2; GM-Tg-cynog-T92557-Ag-1/ GM-Tg-cynog-T92557-Ag-2;
GM-Tg-felg-T92557-Ag-1/ GM-Tg-felg-T92557-Ag-2; GM-Tg-cang-T92557-Ag-1/ GM-Tg-cang-T92557-Ag-2;
GM-Tg-bovg-T92557-Ag-1/ GM-Tg-bovg-T92557-Ag-2; GM-Tg-equg-T92557-Ag-1/ GM-Tg-equg-T92557-Ag-2
Products Name BCAT1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name BCAT1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BCAT1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.