Explore BCAT1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010]
| Target ID |
GM-T92557
|
| Target Name |
BCAT1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
586
|
| Gene ID |
100068713 (Equus caballus), 101097404 (Felis catus), 12035 (Mus musculus), 29592 (Rattus norvegicus)
486633 (Canis lupus familiaris), 505926 (Bos taurus), 586 (Homo sapiens), 707321 (Macaca mulatta)
|
| Target Alternative Names |
BCAT(c),BCAT1,BCATC,BCATc,BCT1,Bcat1,Bcatc,Branched-chain-amino-acid aminotransferase,ECA39,Eca39,MECA39,PNAS121,PP18,cytosolic
|
| Uniprot Accession |
P24288,P54690,P54687
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000020973, ENSMUSG00000030268, ENSCAFG00845013534, ENSBTAG00000013825, ENSG00000060982, ENSMMUG00000012223
|
Pre-made viral vector of BCAT1 cDNA Clones/ORF Plasmid
BCAT1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo586 | Pre-made Human BCAT1/BCT1/PP18 siRNA oligo Duplex | 586 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29592 | Pre-made Rat Bcat1/Bcatc siRNA oligo Duplex | 29592 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12035 | Pre-made Mouse Bcat1/BCATc/Eca39 siRNA oligo Duplex | 12035 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707321 | Pre-made Cynomolgus/Rhesus macaque BCAT1 siRNA oligo Duplex | 707321 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097404 | Pre-made Cat/Feline BCAT1 siRNA oligo Duplex | 101097404 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo486633 | Pre-made Dog/Canine BCAT1 siRNA oligo Duplex | 486633 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo505926 | Pre-made Bovines/Cattle BCAT1 siRNA oligo Duplex | 505926 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068713 | Pre-made Equine/Horse BCAT1 siRNA oligo Duplex | 100068713 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BCAT1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T92557-Ab | Human | Anti-Human BCAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T92557-Ab | Rat | Anti-Rat BCAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T92557-Ab | Mouse | Anti-Mouse BCAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T92557-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BCAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T92557-Ab | Cat/Feline | Anti-Cat/Feline BCAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T92557-Ab | Dog/Canine | Anti-Dog/Canine BCAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T92557-Ab | Bovines/Cattle | Anti-Bovines/Cattle BCAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T92557-Ab | Equine/Horse | Anti-Equine/Horse BCAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
BCAT1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T92557-Ag | Human | Human BCAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T92557-Ag | Rat | Rat BCAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T92557-Ag | Mouse | Mouse BCAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T92557-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BCAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T92557-Ag | Cat/Feline | Cat/Feline BCAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T92557-Ag | Dog/Canine | Dog/Canine BCAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T92557-Ag | Bovines/Cattle | Bovines/Cattle BCAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T92557-Ag | Equine/Horse | Equine/Horse BCAT1 recombinant protein | Mammalian cell | Detail |
