Recombinant multi-species PDE1C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE1C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016]
The Alternative Names of target: 5'-cyclic nucleotide phosphodiesterase 1C,Cam-PDE 1C,DFNA74,Dual specificity calcium/calmodulin-dependent 3',Hcam3,PDE1C,Pde1c,cam-PDE 1C,hCam-3

Target products collectionGo to PDE1C products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T92439-Ag-1/ GM-Tg-hg-T92439-Ag-2 Human PDE1C protein Human
GM-Tg-rg-T92439-Ag-1/ GM-Tg-rg-T92439-Ag-2 Rat PDE1C protein Rat
GM-Tg-mg-T92439-Ag-1/ GM-Tg-mg-T92439-Ag-2 Mouse PDE1C protein Mouse
GM-Tg-cynog-T92439-Ag-1/ GM-Tg-cynog-T92439-Ag-2 Cynomolgus/Rhesus macaque PDE1C protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T92439-Ag-1/ GM-Tg-felg-T92439-Ag-2 Feline PDE1C protein Feline
GM-Tg-cang-T92439-Ag-1/ GM-Tg-cang-T92439-Ag-2 Canine PDE1C protein Canine
GM-Tg-bovg-T92439-Ag-1/ GM-Tg-bovg-T92439-Ag-2 Bovine PDE1C protein Bovine
GM-Tg-equg-T92439-Ag-1/ GM-Tg-equg-T92439-Ag-2 Equine PDE1C protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T92439-Ag-1/ GM-Tg-hg-T92439-Ag-2; GM-Tg-rg-T92439-Ag-1/ GM-Tg-rg-T92439-Ag-2;
GM-Tg-mg-T92439-Ag-1/ GM-Tg-mg-T92439-Ag-2; GM-Tg-cynog-T92439-Ag-1/ GM-Tg-cynog-T92439-Ag-2;
GM-Tg-felg-T92439-Ag-1/ GM-Tg-felg-T92439-Ag-2; GM-Tg-cang-T92439-Ag-1/ GM-Tg-cang-T92439-Ag-2;
GM-Tg-bovg-T92439-Ag-1/ GM-Tg-bovg-T92439-Ag-2; GM-Tg-equg-T92439-Ag-1/ GM-Tg-equg-T92439-Ag-2
Products Name PDE1C protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PDE1C
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE1C protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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