Explore PDE1C gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016]
| Target ID |
GM-T92439
|
| Target Name |
PDE1C
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5137
|
| Gene ID |
100070015 (Equus caballus), 101089682 (Felis catus), 18575 (Mus musculus), 475272 (Canis lupus familiaris)
5137 (Homo sapiens), 526211 (Bos taurus), 693937 (Macaca mulatta), 81742 (Rattus norvegicus)
|
| Target Alternative Names |
5'-cyclic nucleotide phosphodiesterase 1C,Cam-PDE 1C,DFNA74,Dual specificity calcium/calmodulin-dependent 3',Hcam3,PDE1C,Pde1c,cam-PDE 1C,hCam-3
|
| Uniprot Accession |
Q64338,Q14123,Q63421
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction
|
| Gene Ensembl |
ENSECAG00000021914, ENSMUSG00000004347, ENSCAFG00845022048, ENSG00000154678, ENSBTAG00000002739, ENSMMUG00000001625
|
PDE1C siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5137 | Pre-made Human PDE1C/Hcam3/DFNA74 siRNA oligo Duplex | 5137 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81742 | Pre-made Rat Pde1c siRNA oligo Duplex | 81742 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo18575 | Pre-made Mouse Pde1c siRNA oligo Duplex | 18575 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693937 | Pre-made Cynomolgus/Rhesus macaque PDE1C siRNA oligo Duplex | 693937 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089682 | Pre-made Cat/Feline PDE1C siRNA oligo Duplex | 101089682 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475272 | Pre-made Dog/Canine PDE1C siRNA oligo Duplex | 475272 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo526211 | Pre-made Bovines/Cattle PDE1C siRNA oligo Duplex | 526211 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070015 | Pre-made Equine/Horse PDE1C siRNA oligo Duplex | 100070015 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PDE1C antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T92439-Ab | Human | Anti-Human PDE1C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T92439-Ab | Rat | Anti-Rat PDE1C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T92439-Ab | Mouse | Anti-Mouse PDE1C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T92439-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PDE1C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T92439-Ab | Cat/Feline | Anti-Cat/Feline PDE1C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T92439-Ab | Dog/Canine | Anti-Dog/Canine PDE1C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T92439-Ab | Bovines/Cattle | Anti-Bovines/Cattle PDE1C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T92439-Ab | Equine/Horse | Anti-Equine/Horse PDE1C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PDE1C recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T92439-Ag | Human | Human PDE1C recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T92439-Ag | Rat | Rat PDE1C recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T92439-Ag | Mouse | Mouse PDE1C recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T92439-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PDE1C recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T92439-Ag | Cat/Feline | Cat/Feline PDE1C recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T92439-Ag | Dog/Canine | Dog/Canine PDE1C recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T92439-Ag | Bovines/Cattle | Bovines/Cattle PDE1C recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T92439-Ag | Equine/Horse | Equine/Horse PDE1C recombinant protein | Mammalian cell | Detail |
