Recombinant multi-species CREB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CREB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
The Alternative Names of target: 2310001E10Rik,3526402H21Rik,CREB,CREB-1,CREB1,Creb,Creb-1,Creb1,Cyclic AMP-responsive element-binding protein 1,cAMP-responsive element-binding protein 1

Target products collectionGo to CREB1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T92098-Ag-1/ GM-Tg-hg-T92098-Ag-2 Human CREB1 protein Human
GM-Tg-rg-T92098-Ag-1/ GM-Tg-rg-T92098-Ag-2 Rat CREB1 protein Rat
GM-Tg-mg-T92098-Ag-1/ GM-Tg-mg-T92098-Ag-2 Mouse CREB1 protein Mouse
GM-Tg-cynog-T92098-Ag-1/ GM-Tg-cynog-T92098-Ag-2 Cynomolgus/Rhesus macaque CREB1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T92098-Ag-1/ GM-Tg-felg-T92098-Ag-2 Feline CREB1 protein Feline
GM-Tg-cang-T92098-Ag-1/ GM-Tg-cang-T92098-Ag-2 Canine CREB1 protein Canine
GM-Tg-bovg-T92098-Ag-1/ GM-Tg-bovg-T92098-Ag-2 Bovine CREB1 protein Bovine
GM-Tg-equg-T92098-Ag-1/ GM-Tg-equg-T92098-Ag-2 Equine CREB1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T92098-Ag-1/ GM-Tg-hg-T92098-Ag-2; GM-Tg-rg-T92098-Ag-1/ GM-Tg-rg-T92098-Ag-2;
GM-Tg-mg-T92098-Ag-1/ GM-Tg-mg-T92098-Ag-2; GM-Tg-cynog-T92098-Ag-1/ GM-Tg-cynog-T92098-Ag-2;
GM-Tg-felg-T92098-Ag-1/ GM-Tg-felg-T92098-Ag-2; GM-Tg-cang-T92098-Ag-1/ GM-Tg-cang-T92098-Ag-2;
GM-Tg-bovg-T92098-Ag-1/ GM-Tg-bovg-T92098-Ag-2; GM-Tg-equg-T92098-Ag-1/ GM-Tg-equg-T92098-Ag-2
Products Name CREB1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CREB1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CREB1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.