Explore CREB1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
| Target ID |
GM-T92098
|
| Target Name |
CREB1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1385
|
| Gene ID |
100066388 (Equus caballus), 101091299 (Felis catus), 12912 (Mus musculus), 1385 (Homo sapiens)
281713 (Bos taurus), 607922 (Canis lupus familiaris), 708717 (Macaca mulatta), 81646 (Rattus norvegicus)
|
| Target Alternative Names |
2310001E10Rik,3526402H21Rik,CREB,CREB-1,CREB1,Creb,Creb-1,Creb1,Cyclic AMP-responsive element-binding protein 1,cAMP-responsive element-binding protein 1
|
| Uniprot Accession |
Q01147,P16220,P27925,P15337
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
cGMP-PKG signaling pathway, cAMP signaling pathway, PI3K-Akt signaling pathway, Longevity regulating pathway, Adrenergic signaling in cardiomyocytes, Osteoclast differentiation, Antigen processing and presentation, TNF signaling pathway, Circadian entrainment, Cholinergic synapse, Insulin secretion, Melanogenesis, Thyroid hormone synthesis, Renin secretion, Aldosterone synthesis and secretion, Relaxin signaling pathway, Cortisol synthesis and secretion, Parathyroid hormone synthesis, secretion and action, Insulin resistance, Cushing syndrome, Growth hormone synthesis, secretion and action, Cocaine addiction, Amphetamine addiction, Tuberculosis, Hepatitis B, Human cytomegalovirus infection, Human papillomavirus infection, Human T-cell leukemia virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Chemical carcinogenesis - receptor activation, Prostate cancer
|
| Gene Ensembl |
ENSECAG00000013667, ENSMUSG00000025958, ENSG00000118260, ENSBTAG00000005474, ENSCAFG00845022020, ENSMMUG00000022601
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of CREB1 cDNA Clones/ORF Plasmid
CREB1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1385 | Pre-made Human CREB1/CREB/CREB-1 siRNA oligo Duplex | 1385 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81646 | Pre-made Rat Creb1/Creb siRNA oligo Duplex | 81646 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12912 | Pre-made Mouse Creb1/Creb/Creb-1 siRNA oligo Duplex | 12912 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708717 | Pre-made Cynomolgus/Rhesus macaque CREB1 siRNA oligo Duplex | 708717 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091299 | Pre-made Cat/Feline CREB1 siRNA oligo Duplex | 101091299 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo607922 | Pre-made Dog/Canine CREB1 siRNA oligo Duplex | 607922 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281713 | Pre-made Bovines/Cattle CREB1/CREB siRNA oligo Duplex | 281713 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066388 | Pre-made Equine/Horse CREB1 siRNA oligo Duplex | 100066388 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CREB1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T92098-Ab | Human | Anti-Human CREB1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T92098-Ab | Rat | Anti-Rat CREB1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T92098-Ab | Mouse | Anti-Mouse CREB1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T92098-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CREB1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T92098-Ab | Cat/Feline | Anti-Cat/Feline CREB1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T92098-Ab | Dog/Canine | Anti-Dog/Canine CREB1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T92098-Ab | Bovines/Cattle | Anti-Bovines/Cattle CREB1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T92098-Ab | Equine/Horse | Anti-Equine/Horse CREB1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CREB1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T92098-Ag | Human | Human CREB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T92098-Ag | Rat | Rat CREB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T92098-Ag | Mouse | Mouse CREB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T92098-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CREB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T92098-Ag | Cat/Feline | Cat/Feline CREB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T92098-Ag | Dog/Canine | Dog/Canine CREB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T92098-Ag | Bovines/Cattle | Bovines/Cattle CREB1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T92098-Ag | Equine/Horse | Equine/Horse CREB1 recombinant protein | Mammalian cell | Detail |
