Recombinant multi-species MAP3K10/MLK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAP3K10/MLK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008]
The Alternative Names of target: MAP3K10, MLK2,Mitogen-activated protein kinase kinase kinase 10,Mixed lineage kinase 2, Protein kinase MST,MST,MLK2,MEKK10

Target products collectionGo to MAP3K10/MLK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T89323-Ab-1/ GM-Tg-hg-T89323-Ab-2 Human MAP3K10/MLK2 protein Human
GM-Tg-rg-T89323-Ab-1/ GM-Tg-rg-T89323-Ab-2 Rat MAP3K10/MLK2 protein Rat
GM-Tg-mg-T89323-Ab-1/ GM-Tg-mg-T89323-Ab-2 Mouse MAP3K10/MLK2 protein Mouse
GM-Tg-cynog-T89323-Ab-1/ GM-Tg-cynog-T89323-Ab-2 Cynomolgus/Rhesus macaque MAP3K10/MLK2 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T89323-Ab-1/ GM-Tg-felg-T89323-Ab-2 Feline MAP3K10/MLK2 protein Feline
GM-Tg-cang-T89323-Ab-1/ GM-Tg-cang-T89323-Ab-2 Canine MAP3K10/MLK2 protein Canine
GM-Tg-bovg-T89323-Ab-1/ GM-Tg-bovg-T89323-Ab-2 Bovine MAP3K10/MLK2 protein Bovine
GM-Tg-equg-T89323-Ab-1/ GM-Tg-equg-T89323-Ab-2 Equine MAP3K10/MLK2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T89323-Ab-1/ GM-Tg-hg-T89323-Ab-2; GM-Tg-rg-T89323-Ab-1/ GM-Tg-rg-T89323-Ab-2;
GM-Tg-mg-T89323-Ab-1/ GM-Tg-mg-T89323-Ab-2; GM-Tg-cynog-T89323-Ab-1/ GM-Tg-cynog-T89323-Ab-2;
GM-Tg-felg-T89323-Ab-1/ GM-Tg-felg-T89323-Ab-2; GM-Tg-cang-T89323-Ab-1/ GM-Tg-cang-T89323-Ab-2;
GM-Tg-bovg-T89323-Ab-1/ GM-Tg-bovg-T89323-Ab-2; GM-Tg-equg-T89323-Ab-1/ GM-Tg-equg-T89323-Ab-2
Products Name MAP3K10/MLK2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MAP3K10/MLK2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAP3K10/MLK2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.