Explore MAP3K10/MLK2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T89323
|
| Target Name |
MAP3K10/MLK2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4294
|
| Gene ID |
100067981 (Equus caballus), 101089731 (Felis catus), 269881 (Mus musculus), 308463 (Rattus norvegicus)
4294 (Homo sapiens), 484504 (Canis lupus familiaris), 700477 (Macaca mulatta), 781037 (Bos taurus)
|
| Target Alternative Names |
MAP3K10,Map3k10,MST,Mlk2,MLK2,MEKK10
|
| Uniprot Accession |
Q66L42,D3ZG83,Q02779
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
|
| Gene Ensembl |
ENSECAG00000037204, ENSMUSG00000040390, ENSG00000130758, ENSCAFG00845004014, ENSMMUG00000003624, ENSBTAG00000017618
|
| Target Classification |
Kinase
|
Pre-made viral vector of MAP3K10/MLK2 cDNA Clones/ORF Plasmid
MAP3K10/MLK2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4294 | Pre-made Human MAP3K10/MST/MLK2 siRNA oligo Duplex | 4294 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo308463 | Pre-made Rat Map3k10/Mlk2 siRNA oligo Duplex | 308463 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo269881 | Pre-made Mouse Map3k10/MST/Mlk2 siRNA oligo Duplex | 269881 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700477 | Pre-made Cynomolgus/Rhesus macaque MAP3K10 siRNA oligo Duplex | 700477 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089731 | Pre-made Cat/Feline MAP3K10 siRNA oligo Duplex | 101089731 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484504 | Pre-made Dog/Canine MAP3K10 siRNA oligo Duplex | 484504 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo781037 | Pre-made Bovines/Cattle MAP3K10 siRNA oligo Duplex | 781037 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067981 | Pre-made Equine/Horse MAP3K10 siRNA oligo Duplex | 100067981 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MAP3K10/MLK2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T89323-Ab | Human | Anti-Human MAP3K10/MLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T89323-Ab | Rat | Anti-Rat MAP3K10/MLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T89323-Ab | Mouse | Anti-Mouse MAP3K10/MLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T89323-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MAP3K10/MLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T89323-Ab | Cat/Feline | Anti-Cat/Feline MAP3K10/MLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T89323-Ab | Dog/Canine | Anti-Dog/Canine MAP3K10/MLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T89323-Ab | Bovines/Cattle | Anti-Bovines/Cattle MAP3K10/MLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T89323-Ab | Equine/Horse | Anti-Equine/Horse MAP3K10/MLK2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MAP3K10/MLK2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T89323-Ag | Human | Human MAP3K10/MLK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T89323-Ag | Rat | Rat MAP3K10/MLK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T89323-Ag | Mouse | Mouse MAP3K10/MLK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T89323-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MAP3K10/MLK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T89323-Ag | Cat/Feline | Cat/Feline MAP3K10/MLK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T89323-Ag | Dog/Canine | Dog/Canine MAP3K10/MLK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T89323-Ag | Bovines/Cattle | Bovines/Cattle MAP3K10/MLK2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T89323-Ag | Equine/Horse | Equine/Horse MAP3K10/MLK2 recombinant protein | Mammalian cell | Detail |
