Recombinant multi-species MAP2K2/MEK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAP2K2/MEK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: MAP2K2, MEK2,Dual specificity mitogen-activated protein kinase kinase 2,MAP kinase kinase 2, MAPKK 2,ERK activator kinase 2, MAPK/ERK kinase 2 (MEK 2),CFC4,MEK2,MKK2,MAPKK2,PRKMK2

Target products collectionGo to MAP2K2/MEK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T89055-Ab-1/ GM-Tg-hg-T89055-Ab-2 Human MAP2K2/MEK2 protein Human
GM-Tg-rg-T89055-Ab-1/ GM-Tg-rg-T89055-Ab-2 Rat MAP2K2/MEK2 protein Rat
GM-Tg-mg-T89055-Ab-1/ GM-Tg-mg-T89055-Ab-2 Mouse MAP2K2/MEK2 protein Mouse
GM-Tg-cynog-T89055-Ab-1/ GM-Tg-cynog-T89055-Ab-2 Cynomolgus/Rhesus macaque MAP2K2/MEK2 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T89055-Ab-1/ GM-Tg-felg-T89055-Ab-2 Feline MAP2K2/MEK2 protein Feline
GM-Tg-cang-T89055-Ab-1/ GM-Tg-cang-T89055-Ab-2 Canine MAP2K2/MEK2 protein Canine
GM-Tg-bovg-T89055-Ab-1/ GM-Tg-bovg-T89055-Ab-2 Bovine MAP2K2/MEK2 protein Bovine
GM-Tg-equg-T89055-Ab-1/ GM-Tg-equg-T89055-Ab-2 Equine MAP2K2/MEK2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T89055-Ab-1/ GM-Tg-hg-T89055-Ab-2; GM-Tg-rg-T89055-Ab-1/ GM-Tg-rg-T89055-Ab-2;
GM-Tg-mg-T89055-Ab-1/ GM-Tg-mg-T89055-Ab-2; GM-Tg-cynog-T89055-Ab-1/ GM-Tg-cynog-T89055-Ab-2;
GM-Tg-felg-T89055-Ab-1/ GM-Tg-felg-T89055-Ab-2; GM-Tg-cang-T89055-Ab-1/ GM-Tg-cang-T89055-Ab-2;
GM-Tg-bovg-T89055-Ab-1/ GM-Tg-bovg-T89055-Ab-2; GM-Tg-equg-T89055-Ab-1/ GM-Tg-equg-T89055-Ab-2
Products Name MAP2K2/MEK2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MAP2K2/MEK2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAP2K2/MEK2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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