Recombinant multi-species OPA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine OPA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. [provided by RefSeq, Aug 2017]
The Alternative Names of target: 1200011N24Rik,BERHS,Dynamin-like GTPase OPA1,MGM1,MTDPS14,NPG,NTG,OPA1,Opa1,Optic atrophy protein 1,largeG,lilr3,mKIAA0567,mitochondrial

Target products collectionGo to OPA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T88404-Ag-1/ GM-Tg-hg-T88404-Ag-2 Human OPA1 protein Human
GM-Tg-rg-T88404-Ag-1/ GM-Tg-rg-T88404-Ag-2 Rat OPA1 protein Rat
GM-Tg-mg-T88404-Ag-1/ GM-Tg-mg-T88404-Ag-2 Mouse OPA1 protein Mouse
GM-Tg-cynog-T88404-Ag-1/ GM-Tg-cynog-T88404-Ag-2 Cynomolgus/Rhesus macaque OPA1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T88404-Ag-1/ GM-Tg-felg-T88404-Ag-2 Feline OPA1 protein Feline
GM-Tg-cang-T88404-Ag-1/ GM-Tg-cang-T88404-Ag-2 Canine OPA1 protein Canine
GM-Tg-bovg-T88404-Ag-1/ GM-Tg-bovg-T88404-Ag-2 Bovine OPA1 protein Bovine
GM-Tg-equg-T88404-Ag-1/ GM-Tg-equg-T88404-Ag-2 Equine OPA1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T88404-Ag-1/ GM-Tg-hg-T88404-Ag-2; GM-Tg-rg-T88404-Ag-1/ GM-Tg-rg-T88404-Ag-2;
GM-Tg-mg-T88404-Ag-1/ GM-Tg-mg-T88404-Ag-2; GM-Tg-cynog-T88404-Ag-1/ GM-Tg-cynog-T88404-Ag-2;
GM-Tg-felg-T88404-Ag-1/ GM-Tg-felg-T88404-Ag-2; GM-Tg-cang-T88404-Ag-1/ GM-Tg-cang-T88404-Ag-2;
GM-Tg-bovg-T88404-Ag-1/ GM-Tg-bovg-T88404-Ag-2; GM-Tg-equg-T88404-Ag-1/ GM-Tg-equg-T88404-Ag-2
Products Name OPA1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name OPA1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine OPA1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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