Explore OPA1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. [provided by RefSeq, Aug 2017]
| Target ID |
GM-T88404
|
| Target Name |
OPA1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4976
|
| Gene ID |
100059993 (Equus caballus), 101086671 (Felis catus), 171116 (Rattus norvegicus), 477129 (Canis lupus familiaris) 4976 (Homo sapiens), 524142 (Bos taurus), 698540 (Macaca mulatta), 74143 (Mus musculus)
|
| Target Alternative Names |
1200011N24Rik,BERHS,Dynamin-like GTPase OPA1,MGM1,MTDPS14,NPG,NTG,OPA1,Opa1,Optic atrophy protein 1,largeG,lilr3,mKIAA0567,mitochondrial
|
| Uniprot Accession |
Q2TA68,O60313,P58281
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
Prostate Cancer
|
| Gene Ensembl |
ENSECAG00000024248, ENSCAFG00845025222, ENSG00000198836, ENSBTAG00000019514, ENSMMUG00000009765, ENSMUSG00000038084
|
Pre-made viral vector of OPA1 cDNA Clones/ORF Plasmid
OPA1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4976 | Pre-made Human OPA1/NPG/NTG siRNA oligo Duplex | 4976 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo171116 | Pre-made Rat Opa1 siRNA oligo Duplex | 171116 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo74143 | Pre-made Mouse Opa1/lilr3/mKIAA0567 siRNA oligo Duplex | 74143 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698540 | Pre-made Cynomolgus/Rhesus macaque OPA1 siRNA oligo Duplex | 698540 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086671 | Pre-made Cat/Feline OPA1 siRNA oligo Duplex | 101086671 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477129 | Pre-made Dog/Canine OPA1 siRNA oligo Duplex | 477129 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo524142 | Pre-made Bovines/Cattle OPA1 siRNA oligo Duplex | 524142 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059993 | Pre-made Equine/Horse OPA1 siRNA oligo Duplex | 100059993 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
OPA1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T88404-Ab | Human | Anti-Human OPA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T88404-Ab | Rat | Anti-Rat OPA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T88404-Ab | Mouse | Anti-Mouse OPA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T88404-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque OPA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T88404-Ab | Cat/Feline | Anti-Cat/Feline OPA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T88404-Ab | Dog/Canine | Anti-Dog/Canine OPA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T88404-Ab | Bovines/Cattle | Anti-Bovines/Cattle OPA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T88404-Ab | Equine/Horse | Anti-Equine/Horse OPA1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
OPA1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T88404-Ag | Human | Human OPA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T88404-Ag | Rat | Rat OPA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T88404-Ag | Mouse | Mouse OPA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T88404-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque OPA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T88404-Ag | Cat/Feline | Cat/Feline OPA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T88404-Ag | Dog/Canine | Dog/Canine OPA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T88404-Ag | Bovines/Cattle | Bovines/Cattle OPA1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T88404-Ag | Equine/Horse | Equine/Horse OPA1 recombinant protein | Mammalian cell | Detail |