Recombinant multi-species DOT1L/HLNM protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DOT1L/HLNM protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011]
The Alternative Names of target: A630076O07,DOT1,DOT1-like protein,DOT1L,Dot1,Dot1l,H3 lysine-79 specific,HLNM,Histone H3-K79 methyltransferase (H3-K79-HMTase),Histone-lysine N-methyltransferase,KMT4,Lysine N-methyltransferase 4,mDot1

Target products collectionGo to DOT1L/HLNM products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T87686-Ag-1/ GM-Tg-hg-T87686-Ag-2 Human DOT1L/HLNM protein Human
GM-Tg-rg-T87686-Ag-1/ GM-Tg-rg-T87686-Ag-2 Rat DOT1L/HLNM protein Rat
GM-Tg-mg-T87686-Ag-1/ GM-Tg-mg-T87686-Ag-2 Mouse DOT1L/HLNM protein Mouse
GM-Tg-cynog-T87686-Ag-1/ GM-Tg-cynog-T87686-Ag-2 Cynomolgus/Rhesus macaque DOT1L/HLNM protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T87686-Ag-1/ GM-Tg-felg-T87686-Ag-2 Feline DOT1L/HLNM protein Feline
GM-Tg-cang-T87686-Ag-1/ GM-Tg-cang-T87686-Ag-2 Canine DOT1L/HLNM protein Canine
GM-Tg-bovg-T87686-Ag-1/ GM-Tg-bovg-T87686-Ag-2 Bovine DOT1L/HLNM protein Bovine
GM-Tg-equg-T87686-Ag-1/ GM-Tg-equg-T87686-Ag-2 Equine DOT1L/HLNM protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T87686-Ag-1/ GM-Tg-hg-T87686-Ag-2; GM-Tg-rg-T87686-Ag-1/ GM-Tg-rg-T87686-Ag-2;
GM-Tg-mg-T87686-Ag-1/ GM-Tg-mg-T87686-Ag-2; GM-Tg-cynog-T87686-Ag-1/ GM-Tg-cynog-T87686-Ag-2;
GM-Tg-felg-T87686-Ag-1/ GM-Tg-felg-T87686-Ag-2; GM-Tg-cang-T87686-Ag-1/ GM-Tg-cang-T87686-Ag-2;
GM-Tg-bovg-T87686-Ag-1/ GM-Tg-bovg-T87686-Ag-2; GM-Tg-equg-T87686-Ag-1/ GM-Tg-equg-T87686-Ag-2
Products Name DOT1L/HLNM protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name DOT1L/HLNM
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DOT1L/HLNM protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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