Explore DOT1L/HLNM gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011]
| Target ID |
GM-T87686
|
| Target Name |
DOT1L/HLNM
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
84444
|
| Gene ID |
100068506 (Equus caballus), 101101194 (Felis catus), 208266 (Mus musculus), 362831 (Rattus norvegicus)
485073 (Canis lupus familiaris), 510442 (Bos taurus), 710033 (Macaca mulatta), 84444 (Homo sapiens)
|
| Target Alternative Names |
DOT1L,Dot1l,Dot1,KMT4,mDot1,A630076O07,DOT1
|
| Uniprot Accession |
Q8TEK3
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways
|
| Gene Ensembl |
ENSECAG00000013711, ENSMUSG00000061589, ENSCAFG00845012642, ENSBTAG00000009996, ENSMMUG00000010107, ENSG00000104885
|
| Target Classification |
Epigenetic
|
Pre-made viral vector of DOT1L/HLNM cDNA Clones/ORF Plasmid
DOT1L/HLNM siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo84444 | Pre-made Human DOT1L/DOT1/KMT4 siRNA oligo Duplex | 84444 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362831 | Pre-made Rat Dot1l siRNA oligo Duplex | 362831 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo208266 | Pre-made Mouse Dot1l/Dot1/KMT4 siRNA oligo Duplex | 208266 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710033 | Pre-made Cynomolgus/Rhesus macaque DOT1L siRNA oligo Duplex | 710033 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101194 | Pre-made Cat/Feline DOT1L siRNA oligo Duplex | 101101194 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485073 | Pre-made Dog/Canine DOT1L siRNA oligo Duplex | 485073 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo510442 | Pre-made Bovines/Cattle DOT1L siRNA oligo Duplex | 510442 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068506 | Pre-made Equine/Horse DOT1L siRNA oligo Duplex | 100068506 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DOT1L/HLNM antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T87686-Ab | Human | Anti-Human DOT1L/HLNM monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T87686-Ab | Rat | Anti-Rat DOT1L/HLNM monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T87686-Ab | Mouse | Anti-Mouse DOT1L/HLNM monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T87686-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DOT1L/HLNM monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T87686-Ab | Cat/Feline | Anti-Cat/Feline DOT1L/HLNM monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T87686-Ab | Dog/Canine | Anti-Dog/Canine DOT1L/HLNM monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T87686-Ab | Bovines/Cattle | Anti-Bovines/Cattle DOT1L/HLNM monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T87686-Ab | Equine/Horse | Anti-Equine/Horse DOT1L/HLNM monoclonal antibody | mab | Therapeutics Target antibody | Detail |
DOT1L/HLNM recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T87686-Ag | Human | Human DOT1L/HLNM recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T87686-Ag | Rat | Rat DOT1L/HLNM recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T87686-Ag | Mouse | Mouse DOT1L/HLNM recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T87686-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DOT1L/HLNM recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T87686-Ag | Cat/Feline | Cat/Feline DOT1L/HLNM recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T87686-Ag | Dog/Canine | Dog/Canine DOT1L/HLNM recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T87686-Ag | Bovines/Cattle | Bovines/Cattle DOT1L/HLNM recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T87686-Ag | Equine/Horse | Equine/Horse DOT1L/HLNM recombinant protein | Mammalian cell | Detail |
