Recombinant multi-species S100B/S100 Beta protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine S100B/S100 Beta protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
The Alternative Names of target: Bpb,NEF,Protein S100-B,S-100 protein beta chain,S-100 protein subunit beta,S100,S100 Beta,S100 calcium-binding protein B,S100-B,S100B,S100P,S100b,S100beta

Target products collectionGo to S100B/S100 Beta products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T87206-Ag-1/ GM-Tg-hg-T87206-Ag-2 Human S100B/S100 Beta protein Human
GM-Tg-rg-T87206-Ag-1/ GM-Tg-rg-T87206-Ag-2 Rat S100B/S100 Beta protein Rat
GM-Tg-mg-T87206-Ag-1/ GM-Tg-mg-T87206-Ag-2 Mouse S100B/S100 Beta protein Mouse
GM-Tg-cynog-T87206-Ag-1/ GM-Tg-cynog-T87206-Ag-2 Cynomolgus/Rhesus macaque S100B/S100 Beta protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T87206-Ag-1/ GM-Tg-felg-T87206-Ag-2 Feline S100B/S100 Beta protein Feline
GM-Tg-cang-T87206-Ag-1/ GM-Tg-cang-T87206-Ag-2 Canine S100B/S100 Beta protein Canine
GM-Tg-bovg-T87206-Ag-1/ GM-Tg-bovg-T87206-Ag-2 Bovine S100B/S100 Beta protein Bovine
GM-Tg-equg-T87206-Ag-1/ GM-Tg-equg-T87206-Ag-2 Equine S100B/S100 Beta protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T87206-Ag-1/ GM-Tg-hg-T87206-Ag-2; GM-Tg-rg-T87206-Ag-1/ GM-Tg-rg-T87206-Ag-2;
GM-Tg-mg-T87206-Ag-1/ GM-Tg-mg-T87206-Ag-2; GM-Tg-cynog-T87206-Ag-1/ GM-Tg-cynog-T87206-Ag-2;
GM-Tg-felg-T87206-Ag-1/ GM-Tg-felg-T87206-Ag-2; GM-Tg-cang-T87206-Ag-1/ GM-Tg-cang-T87206-Ag-2;
GM-Tg-bovg-T87206-Ag-1/ GM-Tg-bovg-T87206-Ag-2; GM-Tg-equg-T87206-Ag-1/ GM-Tg-equg-T87206-Ag-2
Products Name S100B/S100 Beta protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name S100B/S100 Beta
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine S100B/S100 Beta protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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