Explore S100B/S100 Beta gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T87206
|
| Target Name |
S100B/S100 Beta
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6285
|
| Gene ID |
100054841 (Equus caballus), 101099488 (Felis catus), 20203 (Mus musculus), 25742 (Rattus norvegicus) 491615 (Canis lupus familiaris), 525716 (Bos taurus), 6285 (Homo sapiens), 708117 (Macaca mulatta)
|
| Target Alternative Names |
Bpb,NEF,Protein S100-B,S-100 protein beta chain,S-100 protein subunit beta,S100,S100 Beta,S100 calcium-binding protein B,S100-B,S100B,S100P,S100b,S100beta
|
| Uniprot Accession |
P50114,P04631,P02638,P04271
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target, Diagnostics Biomarker
|
| Disease |
cancer, Prostate Cancer, Diffuse traumatic brain injury, Hypoxic ischemic encephalopathy [HIE]
|
| Gene Ensembl |
ENSECAG00000012395, ENSMUSG00000033208, ENSCAFG00845027676, ENSBTAG00000004777, ENSG00000160307, ENSMMUG00000063077
|
Pre-made viral vector of S100B/S100 Beta cDNA Clones/ORF Plasmid
S100B/S100 Beta siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6285 | Pre-made Human S100B/NEF/S100 siRNA oligo Duplex | 6285 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25742 | Pre-made Rat S100b/S100P siRNA oligo Duplex | 25742 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20203 | Pre-made Mouse S100b/Bpb siRNA oligo Duplex | 20203 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708117 | Pre-made Cynomolgus/Rhesus macaque S100B siRNA oligo Duplex | 708117 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099488 | Pre-made Cat/Feline S100B siRNA oligo Duplex | 101099488 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491615 | Pre-made Dog/Canine S100B siRNA oligo Duplex | 491615 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo525716 | Pre-made Bovines/Cattle S100B siRNA oligo Duplex | 525716 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054841 | Pre-made Equine/Horse S100B siRNA oligo Duplex | 100054841 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
S100B/S100 Beta antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T87206-Ab | Human | Anti-Human S100B/S100 Beta monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-rg-T87206-Ab | Rat | Anti-Rat S100B/S100 Beta monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-mg-T87206-Ab | Mouse | Anti-Mouse S100B/S100 Beta monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cynog-T87206-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque S100B/S100 Beta monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-felg-T87206-Ab | Cat/Feline | Anti-Cat/Feline S100B/S100 Beta monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cang-T87206-Ab | Dog/Canine | Anti-Dog/Canine S100B/S100 Beta monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-bovg-T87206-Ab | Bovines/Cattle | Anti-Bovines/Cattle S100B/S100 Beta monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-equg-T87206-Ab | Equine/Horse | Anti-Equine/Horse S100B/S100 Beta monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
S100B/S100 Beta recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T87206-Ag | Human | Human S100B/S100 Beta recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T87206-Ag | Rat | Rat S100B/S100 Beta recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T87206-Ag | Mouse | Mouse S100B/S100 Beta recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T87206-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque S100B/S100 Beta recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T87206-Ag | Cat/Feline | Cat/Feline S100B/S100 Beta recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T87206-Ag | Dog/Canine | Dog/Canine S100B/S100 Beta recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T87206-Ag | Bovines/Cattle | Bovines/Cattle S100B/S100 Beta recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T87206-Ag | Equine/Horse | Equine/Horse S100B/S100 Beta recombinant protein | Mammalian cell | Detail |