Recombinant multi-species LONP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LONP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]
The Alternative Names of target: 1200017E13Rik,CODASS,LON,LONHs,LONP,LONP1,Lon,Lon protease homolog,Lon protease-like protein (LONP),LonHS,Lonp1,Mitochondrial ATP-dependent protease Lon,PIM1,PRSS15,Prss15,Serine protease 15,hLON,mitochondrial

Target products collectionGo to LONP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T86773-Ag-1/ GM-Tg-hg-T86773-Ag-2 Human LONP1 protein Human
GM-Tg-rg-T86773-Ag-1/ GM-Tg-rg-T86773-Ag-2 Rat LONP1 protein Rat
GM-Tg-mg-T86773-Ag-1/ GM-Tg-mg-T86773-Ag-2 Mouse LONP1 protein Mouse
GM-Tg-cynog-T86773-Ag-1/ GM-Tg-cynog-T86773-Ag-2 Cynomolgus/Rhesus macaque LONP1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T86773-Ag-1/ GM-Tg-felg-T86773-Ag-2 Feline LONP1 protein Feline
GM-Tg-cang-T86773-Ag-1/ GM-Tg-cang-T86773-Ag-2 Canine LONP1 protein Canine
GM-Tg-bovg-T86773-Ag-1/ GM-Tg-bovg-T86773-Ag-2 Bovine LONP1 protein Bovine
GM-Tg-equg-T86773-Ag-1/ GM-Tg-equg-T86773-Ag-2 Equine LONP1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T86773-Ag-1/ GM-Tg-hg-T86773-Ag-2; GM-Tg-rg-T86773-Ag-1/ GM-Tg-rg-T86773-Ag-2;
GM-Tg-mg-T86773-Ag-1/ GM-Tg-mg-T86773-Ag-2; GM-Tg-cynog-T86773-Ag-1/ GM-Tg-cynog-T86773-Ag-2;
GM-Tg-felg-T86773-Ag-1/ GM-Tg-felg-T86773-Ag-2; GM-Tg-cang-T86773-Ag-1/ GM-Tg-cang-T86773-Ag-2;
GM-Tg-bovg-T86773-Ag-1/ GM-Tg-bovg-T86773-Ag-2; GM-Tg-equg-T86773-Ag-1/ GM-Tg-equg-T86773-Ag-2
Products Name LONP1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name LONP1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LONP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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