Recombinant multi-species PPARA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPARA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 4933429D07Rik,NR1C1,Nr1c1,Nuclear receptor subfamily 1 group C member 1,PPAR,PPAR-alpha,PPARA,PPARalpha,Peroxisome proliferator-activated receptor alpha,Ppar,Ppara,hPPAR

Target products collectionGo to PPARA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T86591-Ag-1/ GM-Tg-hg-T86591-Ag-2 Human PPARA protein Human
GM-Tg-rg-T86591-Ag-1/ GM-Tg-rg-T86591-Ag-2 Rat PPARA protein Rat
GM-Tg-mg-T86591-Ag-1/ GM-Tg-mg-T86591-Ag-2 Mouse PPARA protein Mouse
GM-Tg-cynog-T86591-Ag-1/ GM-Tg-cynog-T86591-Ag-2 Cynomolgus/Rhesus macaque PPARA protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T86591-Ag-1/ GM-Tg-felg-T86591-Ag-2 Feline PPARA protein Feline
GM-Tg-cang-T86591-Ag-1/ GM-Tg-cang-T86591-Ag-2 Canine PPARA protein Canine
GM-Tg-bovg-T86591-Ag-1/ GM-Tg-bovg-T86591-Ag-2 Bovine PPARA protein Bovine
GM-Tg-equg-T86591-Ag-1/ GM-Tg-equg-T86591-Ag-2 Equine PPARA protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T86591-Ag-1/ GM-Tg-hg-T86591-Ag-2; GM-Tg-rg-T86591-Ag-1/ GM-Tg-rg-T86591-Ag-2;
GM-Tg-mg-T86591-Ag-1/ GM-Tg-mg-T86591-Ag-2; GM-Tg-cynog-T86591-Ag-1/ GM-Tg-cynog-T86591-Ag-2;
GM-Tg-felg-T86591-Ag-1/ GM-Tg-felg-T86591-Ag-2; GM-Tg-cang-T86591-Ag-1/ GM-Tg-cang-T86591-Ag-2;
GM-Tg-bovg-T86591-Ag-1/ GM-Tg-bovg-T86591-Ag-2; GM-Tg-equg-T86591-Ag-1/ GM-Tg-equg-T86591-Ag-2
Products Name PPARA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PPARA
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PPARA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.