Recombinant multi-species FDPS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FDPS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]
The Alternative Names of target: (2E,6030492I17Rik,6E)-farnesyl diphosphate synthase,Ac2-125,Dimethylallyltranstransferase,FDPS,FPP synthase,FPPS,FPS,Farnesyl diphosphate synthase,Farnesyl pyrophosphate synthase,Fdps,Fdpsl1,Geranyltranstransferase,POROK9,mKIAA1293

Target products collectionGo to FDPS products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T86528-Ag-1/ GM-Tg-hg-T86528-Ag-2 Human FDPS protein Human
GM-Tg-rg-T86528-Ag-1/ GM-Tg-rg-T86528-Ag-2 Rat FDPS protein Rat
GM-Tg-mg-T86528-Ag-1/ GM-Tg-mg-T86528-Ag-2 Mouse FDPS protein Mouse
GM-Tg-cynog-T86528-Ag-1/ GM-Tg-cynog-T86528-Ag-2 Cynomolgus/Rhesus macaque FDPS protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T86528-Ag-1/ GM-Tg-felg-T86528-Ag-2 Feline FDPS protein Feline
GM-Tg-cang-T86528-Ag-1/ GM-Tg-cang-T86528-Ag-2 Canine FDPS protein Canine
GM-Tg-bovg-T86528-Ag-1/ GM-Tg-bovg-T86528-Ag-2 Bovine FDPS protein Bovine
GM-Tg-equg-T86528-Ag-1/ GM-Tg-equg-T86528-Ag-2 Equine FDPS protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T86528-Ag-1/ GM-Tg-hg-T86528-Ag-2; GM-Tg-rg-T86528-Ag-1/ GM-Tg-rg-T86528-Ag-2;
GM-Tg-mg-T86528-Ag-1/ GM-Tg-mg-T86528-Ag-2; GM-Tg-cynog-T86528-Ag-1/ GM-Tg-cynog-T86528-Ag-2;
GM-Tg-felg-T86528-Ag-1/ GM-Tg-felg-T86528-Ag-2; GM-Tg-cang-T86528-Ag-1/ GM-Tg-cang-T86528-Ag-2;
GM-Tg-bovg-T86528-Ag-1/ GM-Tg-bovg-T86528-Ag-2; GM-Tg-equg-T86528-Ag-1/ GM-Tg-equg-T86528-Ag-2
Products Name FDPS protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FDPS
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FDPS protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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