Recombinant multi-species BRD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BRD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
The Alternative Names of target: BRD2,BRD2-IT1,Brd2,Bromodomain-containing protein 2,D17H6S113E,D6S113E,FSH,FSHRG1,FSRG1,Frg-1,Fsrg-1,Fsrg1,NAT,Nat,O27.1.1,RING3,RNF3,Ring3,Rnf3,mKIAA4005

Target products collectionGo to BRD2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T86399-Ag-1/ GM-Tg-hg-T86399-Ag-2 Human BRD2 protein Human
GM-Tg-rg-T86399-Ag-1/ GM-Tg-rg-T86399-Ag-2 Rat BRD2 protein Rat
GM-Tg-mg-T86399-Ag-1/ GM-Tg-mg-T86399-Ag-2 Mouse BRD2 protein Mouse
GM-Tg-cynog-T86399-Ag-1/ GM-Tg-cynog-T86399-Ag-2 Cynomolgus/Rhesus macaque BRD2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T86399-Ag-1/ GM-Tg-felg-T86399-Ag-2 Feline BRD2 protein Feline
GM-Tg-cang-T86399-Ag-1/ GM-Tg-cang-T86399-Ag-2 Canine BRD2 protein Canine
GM-Tg-bovg-T86399-Ag-1/ GM-Tg-bovg-T86399-Ag-2 Bovine BRD2 protein Bovine
GM-Tg-equg-T86399-Ag-1/ GM-Tg-equg-T86399-Ag-2 Equine BRD2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T86399-Ag-1/ GM-Tg-hg-T86399-Ag-2; GM-Tg-rg-T86399-Ag-1/ GM-Tg-rg-T86399-Ag-2;
GM-Tg-mg-T86399-Ag-1/ GM-Tg-mg-T86399-Ag-2; GM-Tg-cynog-T86399-Ag-1/ GM-Tg-cynog-T86399-Ag-2;
GM-Tg-felg-T86399-Ag-1/ GM-Tg-felg-T86399-Ag-2; GM-Tg-cang-T86399-Ag-1/ GM-Tg-cang-T86399-Ag-2;
GM-Tg-bovg-T86399-Ag-1/ GM-Tg-bovg-T86399-Ag-2; GM-Tg-equg-T86399-Ag-1/ GM-Tg-equg-T86399-Ag-2
Products Name BRD2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name BRD2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BRD2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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