Explore BRD2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
| Target ID |
GM-T86399
|
| Target Name |
BRD2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6046
|
| Gene ID |
100052542 (Equus caballus), 111556174 (Felis catus), 14312 (Mus musculus), 294276 (Rattus norvegicus)
474868 (Canis lupus familiaris), 505358 (Bos taurus), 6046 (Homo sapiens), 717893 (Macaca mulatta)
|
| Target Alternative Names |
BRD2,BRD2-IT1,Brd2,Bromodomain-containing protein 2,D17H6S113E,D6S113E,FSH,FSHRG1,FSRG1,Frg-1,Fsrg-1,Fsrg1,NAT,Nat,O27.1.1,RING3,RNF3,Ring3,Rnf3,mKIAA4005
|
| Uniprot Accession |
Q7JJ13,Q6MGA9,Q5TJG6,Q32S26,P25440
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target, Diagnostics Biomarker
|
| Gene Ensembl |
ENSECAG00000012089, ENSMUSG00000024335, ENSCAFG00845018726, ENSBTAG00000011074, ENSG00000204256, ENSMMUG00000023138
|
| Target Classification |
Epigenetic
|
Pre-made viral vector of BRD2 cDNA Clones/ORF Plasmid
BRD2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6046 | Pre-made Human BRD2/FSH/NAT siRNA oligo Duplex | 6046 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo294276 | Pre-made Rat Brd2/Ring3 siRNA oligo Duplex | 294276 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14312 | Pre-made Mouse Brd2/Nat/Rnf3 siRNA oligo Duplex | 14312 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717893 | Pre-made Cynomolgus/Rhesus macaque BRD2 siRNA oligo Duplex | 717893 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111556174 | Pre-made Cat/Feline BRD2 siRNA oligo Duplex | 111556174 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474868 | Pre-made Dog/Canine BRD2 siRNA oligo Duplex | 474868 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo505358 | Pre-made Bovines/Cattle BRD2 siRNA oligo Duplex | 505358 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100052542 | Pre-made Equine/Horse BRD2 siRNA oligo Duplex | 100052542 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BRD2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T86399-Ab | Human | Anti-Human BRD2 monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-rg-T86399-Ab | Rat | Anti-Rat BRD2 monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-mg-T86399-Ab | Mouse | Anti-Mouse BRD2 monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cynog-T86399-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BRD2 monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-felg-T86399-Ab | Cat/Feline | Anti-Cat/Feline BRD2 monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cang-T86399-Ab | Dog/Canine | Anti-Dog/Canine BRD2 monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-bovg-T86399-Ab | Bovines/Cattle | Anti-Bovines/Cattle BRD2 monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-equg-T86399-Ab | Equine/Horse | Anti-Equine/Horse BRD2 monoclonal antibody | mab | Therapeutics Target antibody, Diagnostic target antibody | Detail |
BRD2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T86399-Ag | Human | Human BRD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T86399-Ag | Rat | Rat BRD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T86399-Ag | Mouse | Mouse BRD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T86399-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BRD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T86399-Ag | Cat/Feline | Cat/Feline BRD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T86399-Ag | Dog/Canine | Dog/Canine BRD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T86399-Ag | Bovines/Cattle | Bovines/Cattle BRD2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T86399-Ag | Equine/Horse | Equine/Horse BRD2 recombinant protein | Mammalian cell | Detail |
