Recombinant multi-species TPH2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPH2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016]
The Alternative Names of target: ADHD7,NTPH,Neuronal tryptophan hydroxylase,Ntph,TPH2,Tph2,Tryptophan 5-hydroxylase 2,Tryptophan 5-monooxygenase 2

Target products collectionGo to TPH2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T85915-Ag-1/ GM-Tg-hg-T85915-Ag-2 Human TPH2 protein Human
GM-Tg-rg-T85915-Ag-1/ GM-Tg-rg-T85915-Ag-2 Rat TPH2 protein Rat
GM-Tg-mg-T85915-Ag-1/ GM-Tg-mg-T85915-Ag-2 Mouse TPH2 protein Mouse
GM-Tg-cynog-T85915-Ag-1/ GM-Tg-cynog-T85915-Ag-2 Cynomolgus/Rhesus macaque TPH2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T85915-Ag-1/ GM-Tg-felg-T85915-Ag-2 Feline TPH2 protein Feline
GM-Tg-cang-T85915-Ag-1/ GM-Tg-cang-T85915-Ag-2 Canine TPH2 protein Canine
GM-Tg-bovg-T85915-Ag-1/ GM-Tg-bovg-T85915-Ag-2 Bovine TPH2 protein Bovine
GM-Tg-equg-T85915-Ag-1/ GM-Tg-equg-T85915-Ag-2 Equine TPH2 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T85915-Ag-1/ GM-Tg-hg-T85915-Ag-2; GM-Tg-rg-T85915-Ag-1/ GM-Tg-rg-T85915-Ag-2;
GM-Tg-mg-T85915-Ag-1/ GM-Tg-mg-T85915-Ag-2; GM-Tg-cynog-T85915-Ag-1/ GM-Tg-cynog-T85915-Ag-2;
GM-Tg-felg-T85915-Ag-1/ GM-Tg-felg-T85915-Ag-2; GM-Tg-cang-T85915-Ag-1/ GM-Tg-cang-T85915-Ag-2;
GM-Tg-bovg-T85915-Ag-1/ GM-Tg-bovg-T85915-Ag-2; GM-Tg-equg-T85915-Ag-1/ GM-Tg-equg-T85915-Ag-2
Products Name TPH2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TPH2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TPH2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.