Explore TPH2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016]
| Target ID |
GM-T85915
|
| Target Name |
TPH2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
121278
|
| Gene ID |
100009684 (Equus caballus), 100336620 (Bos taurus), 101082165 (Felis catus), 121278 (Homo sapiens)
216343 (Mus musculus), 317675 (Rattus norvegicus), 481165 (Canis lupus familiaris), 664730 (Macaca mulatta)
|
| Target Alternative Names |
ADHD7,NTPH,Neuronal tryptophan hydroxylase,Ntph,TPH2,Tph2,Tryptophan 5-hydroxylase 2,Tryptophan 5-monooxygenase 2
|
| Uniprot Accession |
Q0EAB8,Q8IWU9,Q8CGV2,Q8CGU9,Q2HZ26
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Serotonergic synapse
|
| Gene Ensembl |
ENSECAG00000013175, ENSBTAG00000020792, ENSG00000139287, ENSMUSG00000006764, ENSCAFG00845024186, ENSMMUG00000007730
|
Pre-made viral vector of TPH2 cDNA Clones/ORF Plasmid
TPH2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo121278 | Pre-made Human TPH2/NTPH/ADHD7 siRNA oligo Duplex | 121278 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo317675 | Pre-made Rat Tph2/Ntph siRNA oligo Duplex | 317675 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo216343 | Pre-made Mouse Tph2/Ntph siRNA oligo Duplex | 216343 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo664730 | Pre-made Cynomolgus/Rhesus macaque TPH2 siRNA oligo Duplex | 664730 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082165 | Pre-made Cat/Feline TPH2 siRNA oligo Duplex | 101082165 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481165 | Pre-made Dog/Canine TPH2 siRNA oligo Duplex | 481165 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100336620 | Pre-made Bovines/Cattle TPH2 siRNA oligo Duplex | 100336620 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100009684 | Pre-made Equine/Horse TPH2 siRNA oligo Duplex | 100009684 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TPH2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T85915-Ab | Human | Anti-Human TPH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T85915-Ab | Rat | Anti-Rat TPH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T85915-Ab | Mouse | Anti-Mouse TPH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T85915-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TPH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T85915-Ab | Cat/Feline | Anti-Cat/Feline TPH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T85915-Ab | Dog/Canine | Anti-Dog/Canine TPH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T85915-Ab | Bovines/Cattle | Anti-Bovines/Cattle TPH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T85915-Ab | Equine/Horse | Anti-Equine/Horse TPH2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
TPH2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T85915-Ag | Human | Human TPH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T85915-Ag | Rat | Rat TPH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T85915-Ag | Mouse | Mouse TPH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T85915-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TPH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T85915-Ag | Cat/Feline | Cat/Feline TPH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T85915-Ag | Dog/Canine | Dog/Canine TPH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T85915-Ag | Bovines/Cattle | Bovines/Cattle TPH2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T85915-Ag | Equine/Horse | Equine/Horse TPH2 recombinant protein | Mammalian cell | Detail |
