Recombinant multi-species cIAP1/BIRC2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine cIAP1/BIRC2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
The Alternative Names of target: API1,Api1,Api2,BIRC2,Baculoviral IAP repeat-containing protein 2,Birc2,Birc3,C-IAP1,C330006D17Rik,Cellular inhibitor of apoptosis 1 (C-IAP1),HIAP1,HIAP2,Hiap-2,IAP homolog B,IAP1,IAP2,Inhibitor of apoptosis protein 2 (hIAP-2,MIAP1,MIAP2,MIHB,MIHC,RING finger protein 48,RING-type E3 ubiquitin transferase BIRC2,RNF48,TNFR2-TRAF-signaling complex protein 2,c-IAP1,cIAP1,cIAP2,hIAP2),mcIAP1,rIAP1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T84780-Ag-1/ GM-Tg-hg-T84780-Ag-2 | Human cIAP1/BIRC2 protein | Human |
| GM-Tg-rg-T84780-Ag-1/ GM-Tg-rg-T84780-Ag-2 | Rat cIAP1/BIRC2 protein | Rat |
| GM-Tg-mg-T84780-Ag-1/ GM-Tg-mg-T84780-Ag-2 | Mouse cIAP1/BIRC2 protein | Mouse |
| GM-Tg-cynog-T84780-Ag-1/ GM-Tg-cynog-T84780-Ag-2 | Cynomolgus/Rhesus macaque cIAP1/BIRC2 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T84780-Ag-1/ GM-Tg-felg-T84780-Ag-2 | Feline cIAP1/BIRC2 protein | Feline |
| GM-Tg-cang-T84780-Ag-1/ GM-Tg-cang-T84780-Ag-2 | Canine cIAP1/BIRC2 protein | Canine |
| GM-Tg-bovg-T84780-Ag-1/ GM-Tg-bovg-T84780-Ag-2 | Bovine cIAP1/BIRC2 protein | Bovine |
| GM-Tg-equg-T84780-Ag-1/ GM-Tg-equg-T84780-Ag-2 | Equine cIAP1/BIRC2 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T84780-Ag-1/ GM-Tg-hg-T84780-Ag-2;
GM-Tg-rg-T84780-Ag-1/ GM-Tg-rg-T84780-Ag-2;
GM-Tg-mg-T84780-Ag-1/ GM-Tg-mg-T84780-Ag-2; GM-Tg-cynog-T84780-Ag-1/ GM-Tg-cynog-T84780-Ag-2; GM-Tg-felg-T84780-Ag-1/ GM-Tg-felg-T84780-Ag-2; GM-Tg-cang-T84780-Ag-1/ GM-Tg-cang-T84780-Ag-2; GM-Tg-bovg-T84780-Ag-1/ GM-Tg-bovg-T84780-Ag-2; GM-Tg-equg-T84780-Ag-1/ GM-Tg-equg-T84780-Ag-2 |
| Products Name | cIAP1/BIRC2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | cIAP1/BIRC2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine cIAP1/BIRC2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.