Explore cIAP1/BIRC2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
| Target ID |
GM-T84780
|
| Target Name |
cIAP1/BIRC2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
329
|
| Gene ID |
100061273 (Equus caballus), 101101663 (Felis catus), 11797 (Mus musculus), 329 (Homo sapiens)
479464 (Canis lupus familiaris), 539314 (Bos taurus), 60371 (Rattus norvegicus), 702592 (Macaca mulatta)
|
| Target Alternative Names |
API1,Api1,Api2,BIRC2,Baculoviral IAP repeat-containing protein 2,Birc2,Birc3,C-IAP1,C330006D17Rik,Cellular inhibitor of apoptosis 1 (C-IAP1),HIAP1,HIAP2,Hiap-2,IAP homolog B,IAP1,IAP2,Inhibitor of apoptosis protein 2 (hIAP-2,MIAP1,MIAP2,MIHB,MIHC,RING finger protein 48,RING-type E3 ubiquitin transferase BIRC2,RNF48,TNFR2-TRAF-signaling complex protein 2,c-IAP1,cIAP1,cIAP2,hIAP2),mcIAP1,rIAP1
|
| Uniprot Accession |
Q62210,Q13490
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
NF-kappa B signaling pathway, Apoptosis, Apoptosis - multiple species, Hippo signaling pathway, Focal adhesion, NOD-like receptor signaling pathway, TNF signaling pathway, Toxoplasmosis, Pathways in cancer, Small cell lung cancer
|
| Gene Ensembl |
ENSECAG00000012229, ENSMUSG00000057367, ENSG00000110330, ENSCAFG00845001046, ENSBTAG00000035735, ENSMMUG00000003400
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of cIAP1/BIRC2 cDNA Clones/ORF Plasmid
cIAP1/BIRC2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo329 | Pre-made Human BIRC2/API1/MIHB siRNA oligo Duplex | 329 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60371 | Pre-made Rat Birc2/Api2/rIAP1 siRNA oligo Duplex | 60371 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11797 | Pre-made Mouse Birc2/Api1/Api2 siRNA oligo Duplex | 11797 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo702592 | Pre-made Cynomolgus/Rhesus macaque BIRC2 siRNA oligo Duplex | 702592 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101663 | Pre-made Cat/Feline BIRC2 siRNA oligo Duplex | 101101663 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479464 | Pre-made Dog/Canine BIRC2 siRNA oligo Duplex | 479464 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539314 | Pre-made Bovines/Cattle BIRC2 siRNA oligo Duplex | 539314 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061273 | Pre-made Equine/Horse BIRC2 siRNA oligo Duplex | 100061273 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
cIAP1/BIRC2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T84780-Ab | Human | Anti-Human cIAP1/BIRC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T84780-Ab | Rat | Anti-Rat cIAP1/BIRC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T84780-Ab | Mouse | Anti-Mouse cIAP1/BIRC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T84780-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque cIAP1/BIRC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T84780-Ab | Cat/Feline | Anti-Cat/Feline cIAP1/BIRC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T84780-Ab | Dog/Canine | Anti-Dog/Canine cIAP1/BIRC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T84780-Ab | Bovines/Cattle | Anti-Bovines/Cattle cIAP1/BIRC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T84780-Ab | Equine/Horse | Anti-Equine/Horse cIAP1/BIRC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
cIAP1/BIRC2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T84780-Ag | Human | Human cIAP1/BIRC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T84780-Ag | Rat | Rat cIAP1/BIRC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T84780-Ag | Mouse | Mouse cIAP1/BIRC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T84780-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque cIAP1/BIRC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T84780-Ag | Cat/Feline | Cat/Feline cIAP1/BIRC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T84780-Ag | Dog/Canine | Dog/Canine cIAP1/BIRC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T84780-Ag | Bovines/Cattle | Bovines/Cattle cIAP1/BIRC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T84780-Ag | Equine/Horse | Equine/Horse cIAP1/BIRC2 recombinant protein | Mammalian cell | Detail |
