Recombinant multi-species UCP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine UCP2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [provided by RefSeq, Jul 2008]
The Alternative Names of target: BMIQ4,Dicarboxylate carrier SLC25A8,Mitochondrial uncoupling protein 2 (UCP 2),SLC25A8,Slc25a8,Solute carrier family 25 member 8,UCP 2,UCP2,UCPH,Ucp2

Target products collectionGo to UCP2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T84560-Ag-1/ GM-Tg-hg-T84560-Ag-2 Human UCP2 protein Human
GM-Tg-rg-T84560-Ag-1/ GM-Tg-rg-T84560-Ag-2 Rat UCP2 protein Rat
GM-Tg-mg-T84560-Ag-1/ GM-Tg-mg-T84560-Ag-2 Mouse UCP2 protein Mouse
GM-Tg-cynog-T84560-Ag-1/ GM-Tg-cynog-T84560-Ag-2 Cynomolgus/Rhesus macaque UCP2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T84560-Ag-1/ GM-Tg-felg-T84560-Ag-2 Feline UCP2 protein Feline
GM-Tg-cang-T84560-Ag-1/ GM-Tg-cang-T84560-Ag-2 Canine UCP2 protein Canine
GM-Tg-bovg-T84560-Ag-1/ GM-Tg-bovg-T84560-Ag-2 Bovine UCP2 protein Bovine
GM-Tg-equg-T84560-Ag-1/ GM-Tg-equg-T84560-Ag-2 Equine UCP2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T84560-Ag-1/ GM-Tg-hg-T84560-Ag-2; GM-Tg-rg-T84560-Ag-1/ GM-Tg-rg-T84560-Ag-2;
GM-Tg-mg-T84560-Ag-1/ GM-Tg-mg-T84560-Ag-2; GM-Tg-cynog-T84560-Ag-1/ GM-Tg-cynog-T84560-Ag-2;
GM-Tg-felg-T84560-Ag-1/ GM-Tg-felg-T84560-Ag-2; GM-Tg-cang-T84560-Ag-1/ GM-Tg-cang-T84560-Ag-2;
GM-Tg-bovg-T84560-Ag-1/ GM-Tg-bovg-T84560-Ag-2; GM-Tg-equg-T84560-Ag-1/ GM-Tg-equg-T84560-Ag-2
Products Name UCP2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name UCP2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine UCP2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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