Recombinant multi-species CACNA2D1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CACNA2D1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. [provided by RefSeq, Nov 2014]
The Alternative Names of target: CACNA2,CACNA2D1,CACNL2A,CCHL2A,CCHLA2,Ca(v)alpha2delta1,Cacna2,Cacna2d1,Cchl2a,DEE110,DHSCCA,LINC01112,Voltage-dependent calcium channel subunit alpha-2/delta-1,Voltage-gated calcium channel subunit alpha-2/delta-1,lncRNA-N3
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T84316-Ag-1/ GM-Tg-hg-T84316-Ag-2 | Human CACNA2D1 protein | Human |
| GM-Tg-rg-T84316-Ag-1/ GM-Tg-rg-T84316-Ag-2 | Rat CACNA2D1 protein | Rat |
| GM-Tg-mg-T84316-Ag-1/ GM-Tg-mg-T84316-Ag-2 | Mouse CACNA2D1 protein | Mouse |
| GM-Tg-cynog-T84316-Ag-1/ GM-Tg-cynog-T84316-Ag-2 | Cynomolgus/Rhesus macaque CACNA2D1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T84316-Ag-1/ GM-Tg-felg-T84316-Ag-2 | Feline CACNA2D1 protein | Feline |
| GM-Tg-cang-T84316-Ag-1/ GM-Tg-cang-T84316-Ag-2 | Canine CACNA2D1 protein | Canine |
| GM-Tg-bovg-T84316-Ag-1/ GM-Tg-bovg-T84316-Ag-2 | Bovine CACNA2D1 protein | Bovine |
| GM-Tg-equg-T84316-Ag-1/ GM-Tg-equg-T84316-Ag-2 | Equine CACNA2D1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T84316-Ag-1/ GM-Tg-hg-T84316-Ag-2;
GM-Tg-rg-T84316-Ag-1/ GM-Tg-rg-T84316-Ag-2;
GM-Tg-mg-T84316-Ag-1/ GM-Tg-mg-T84316-Ag-2; GM-Tg-cynog-T84316-Ag-1/ GM-Tg-cynog-T84316-Ag-2; GM-Tg-felg-T84316-Ag-1/ GM-Tg-felg-T84316-Ag-2; GM-Tg-cang-T84316-Ag-1/ GM-Tg-cang-T84316-Ag-2; GM-Tg-bovg-T84316-Ag-1/ GM-Tg-bovg-T84316-Ag-2; GM-Tg-equg-T84316-Ag-1/ GM-Tg-equg-T84316-Ag-2 |
| Products Name | CACNA2D1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CACNA2D1 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CACNA2D1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.