Recombinant multi-species CACNA2D1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CACNA2D1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. [provided by RefSeq, Nov 2014]
The Alternative Names of target: CACNA2,CACNA2D1,CACNL2A,CCHL2A,CCHLA2,Ca(v)alpha2delta1,Cacna2,Cacna2d1,Cchl2a,DEE110,DHSCCA,LINC01112,Voltage-dependent calcium channel subunit alpha-2/delta-1,Voltage-gated calcium channel subunit alpha-2/delta-1,lncRNA-N3

Target products collectionGo to CACNA2D1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T84316-Ag-1/ GM-Tg-hg-T84316-Ag-2 Human CACNA2D1 protein Human
GM-Tg-rg-T84316-Ag-1/ GM-Tg-rg-T84316-Ag-2 Rat CACNA2D1 protein Rat
GM-Tg-mg-T84316-Ag-1/ GM-Tg-mg-T84316-Ag-2 Mouse CACNA2D1 protein Mouse
GM-Tg-cynog-T84316-Ag-1/ GM-Tg-cynog-T84316-Ag-2 Cynomolgus/Rhesus macaque CACNA2D1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T84316-Ag-1/ GM-Tg-felg-T84316-Ag-2 Feline CACNA2D1 protein Feline
GM-Tg-cang-T84316-Ag-1/ GM-Tg-cang-T84316-Ag-2 Canine CACNA2D1 protein Canine
GM-Tg-bovg-T84316-Ag-1/ GM-Tg-bovg-T84316-Ag-2 Bovine CACNA2D1 protein Bovine
GM-Tg-equg-T84316-Ag-1/ GM-Tg-equg-T84316-Ag-2 Equine CACNA2D1 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T84316-Ag-1/ GM-Tg-hg-T84316-Ag-2; GM-Tg-rg-T84316-Ag-1/ GM-Tg-rg-T84316-Ag-2;
GM-Tg-mg-T84316-Ag-1/ GM-Tg-mg-T84316-Ag-2; GM-Tg-cynog-T84316-Ag-1/ GM-Tg-cynog-T84316-Ag-2;
GM-Tg-felg-T84316-Ag-1/ GM-Tg-felg-T84316-Ag-2; GM-Tg-cang-T84316-Ag-1/ GM-Tg-cang-T84316-Ag-2;
GM-Tg-bovg-T84316-Ag-1/ GM-Tg-bovg-T84316-Ag-2; GM-Tg-equg-T84316-Ag-1/ GM-Tg-equg-T84316-Ag-2
Products Name CACNA2D1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CACNA2D1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CACNA2D1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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