Explore CACNA2D1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. [provided by RefSeq, Nov 2014]
| Target ID |
GM-T84316
|
| Target Name |
CACNA2D1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
781
|
| Gene ID |
100057533 (Equus caballus), 101099450 (Felis catus), 12293 (Mus musculus), 25399 (Rattus norvegicus)
282608 (Bos taurus), 610342 (Canis lupus familiaris), 708215 (Macaca mulatta), 781 (Homo sapiens)
|
| Target Alternative Names |
CACNA2D1,Cacna2d1,Cacna2,Cchl2a,Ca(v)alpha2delta1,CCHLA2,DHSCCA,CACNA2,CCHL2A,DEE110,CACNL2A,LINC01112,lncRNA-N3
|
| Uniprot Accession |
O08532,P54290,P54289
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
MAPK signaling pathway, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000010809, ENSMUSG00000040118, ENSBTAG00000020569, ENSCAFG00845026601, ENSMMUG00000030244, ENSG00000153956
|
| Target Classification |
|
CACNA2D1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo781 | Pre-made Human CACNA2D1/CACNA2/CCHL2A siRNA oligo Duplex | 781 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25399 | Pre-made Rat Cacna2d1/CCHLA2/Cacna2 siRNA oligo Duplex | 25399 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12293 | Pre-made Mouse Cacna2d1/Cacna2/Cchl2a siRNA oligo Duplex | 12293 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708215 | Pre-made Cynomolgus/Rhesus macaque CACNA2D1 siRNA oligo Duplex | 708215 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099450 | Pre-made Cat/Feline CACNA2D1 siRNA oligo Duplex | 101099450 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo610342 | Pre-made Dog/Canine CACNA2D1 siRNA oligo Duplex | 610342 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282608 | Pre-made Bovines/Cattle CACNA2D1 siRNA oligo Duplex | 282608 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057533 | Pre-made Equine/Horse CACNA2D1 siRNA oligo Duplex | 100057533 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CACNA2D1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T84316-Ab | Human | Anti-Human CACNA2D1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T84316-Ab | Rat | Anti-Rat CACNA2D1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T84316-Ab | Mouse | Anti-Mouse CACNA2D1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T84316-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CACNA2D1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T84316-Ab | Cat/Feline | Anti-Cat/Feline CACNA2D1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T84316-Ab | Dog/Canine | Anti-Dog/Canine CACNA2D1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T84316-Ab | Bovines/Cattle | Anti-Bovines/Cattle CACNA2D1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T84316-Ab | Equine/Horse | Anti-Equine/Horse CACNA2D1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CACNA2D1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T84316-Ag | Human | Human CACNA2D1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T84316-Ag | Rat | Rat CACNA2D1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T84316-Ag | Mouse | Mouse CACNA2D1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T84316-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CACNA2D1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T84316-Ag | Cat/Feline | Cat/Feline CACNA2D1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T84316-Ag | Dog/Canine | Dog/Canine CACNA2D1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T84316-Ag | Bovines/Cattle | Bovines/Cattle CACNA2D1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T84316-Ag | Equine/Horse | Equine/Horse CACNA2D1 recombinant protein | Mammalian cell | Detail |
