Recombinant multi-species USP8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine USP8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
The Alternative Names of target: Deubiquitinating enzyme 8,HumORF8,PITA4,SPG59,UBPY,USP8,Ubiquitin carboxyl-terminal hydrolase 8,Ubiquitin isopeptidase Y (hUBPy),Ubiquitin thioesterase 8,Ubiquitin-specific-processing protease 8,Ubpy,Usp8,mKIAA0055

Target products collectionGo to USP8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T83982-Ag-1/ GM-Tg-hg-T83982-Ag-2 Human USP8 protein Human
GM-Tg-rg-T83982-Ag-1/ GM-Tg-rg-T83982-Ag-2 Rat USP8 protein Rat
GM-Tg-mg-T83982-Ag-1/ GM-Tg-mg-T83982-Ag-2 Mouse USP8 protein Mouse
GM-Tg-cynog-T83982-Ag-1/ GM-Tg-cynog-T83982-Ag-2 Cynomolgus/Rhesus macaque USP8 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T83982-Ag-1/ GM-Tg-felg-T83982-Ag-2 Feline USP8 protein Feline
GM-Tg-cang-T83982-Ag-1/ GM-Tg-cang-T83982-Ag-2 Canine USP8 protein Canine
GM-Tg-bovg-T83982-Ag-1/ GM-Tg-bovg-T83982-Ag-2 Bovine USP8 protein Bovine
GM-Tg-equg-T83982-Ag-1/ GM-Tg-equg-T83982-Ag-2 Equine USP8 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T83982-Ag-1/ GM-Tg-hg-T83982-Ag-2; GM-Tg-rg-T83982-Ag-1/ GM-Tg-rg-T83982-Ag-2;
GM-Tg-mg-T83982-Ag-1/ GM-Tg-mg-T83982-Ag-2; GM-Tg-cynog-T83982-Ag-1/ GM-Tg-cynog-T83982-Ag-2;
GM-Tg-felg-T83982-Ag-1/ GM-Tg-felg-T83982-Ag-2; GM-Tg-cang-T83982-Ag-1/ GM-Tg-cang-T83982-Ag-2;
GM-Tg-bovg-T83982-Ag-1/ GM-Tg-bovg-T83982-Ag-2; GM-Tg-equg-T83982-Ag-1/ GM-Tg-equg-T83982-Ag-2
Products Name USP8 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name USP8
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine USP8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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