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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a protein that belongs to the ubiquitin-specific processing protease family of proteins. The encoded protein is thought to regulate the morphology of the endosome by ubiquitination of proteins on this organelle and is involved in cargo sorting and membrane trafficking at the early endosome stage. This protein is required for the cell to enter the S phase of the cell cycle and also functions as a positive regulator in the Hedgehog signaling pathway in development. Pseudogenes of this gene are present on chromosomes 2 and 6. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Target ID |
GM-T83982
|
Target Name |
USP8
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
9101
|
Gene ID |
100055443 (Equus caballus), 101095663 (Felis catus), 296121 (Rattus norvegicus), 478299 (Canis lupus familiaris) 538743 (Bos taurus), 715523 (Macaca mulatta), 84092 (Mus musculus), 9101 (Homo sapiens)
|
Target Alternative Names |
Deubiquitinating enzyme 8,HumORF8,PITA4,SPG59,UBPY,USP8,Ubiquitin carboxyl-terminal hydrolase 8,Ubiquitin isopeptidase Y (hUBPy),Ubiquitin thioesterase 8,Ubiquitin-specific-processing protease 8,Ubpy,Usp8,mKIAA0055
|
Uniprot Accession |
Q80U87,P40818
|
Uniprot Entry Name |
|
Protein Sub-location |
Introcelluar Protein
|
Category |
Therapeutics Target
|
Disease |
|
Disease from KEGG |
Cushing syndrome
|
Gene Ensembl |
ENSECAG00000006611, ENSCAFG00845023888, ENSBTAG00000011916, ENSMMUG00000014884, ENSMUSG00000027363, ENSG00000138592
|
Target Classification |
|
Pre-made viral vector of USP8 cDNA Clones/ORF Plasmid
USP8 siRNA/miRNA/oligo for RNA interfence (RNAi)
Cat No. | Product Name | GeneID | Species | Grade | Detail |
---|
pGMoligo9101 | Pre-made Human USP8/UBPY/PITA4 siRNA oligo Duplex | 9101 | Human | In-vitro grade; in-vivo grade | Detail |
pGMoligo296121 | Pre-made Rat Usp8 siRNA oligo Duplex | 296121 | Rat | In-vitro grade; in-vivo grade | Detail |
pGMoligo84092 | Pre-made Mouse Usp8/Ubpy/mKIAA0055 siRNA oligo Duplex | 84092 | Mouse | In-vitro grade; in-vivo grade | Detail |
pGMoligo715523 | Pre-made Cynomolgus/Rhesus macaque USP8 siRNA oligo Duplex | 715523 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
pGMoligo101095663 | Pre-made Cat/Feline USP8 siRNA oligo Duplex | 101095663 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
pGMoligo478299 | Pre-made Dog/Canine USP8 siRNA oligo Duplex | 478299 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
pGMoligo538743 | Pre-made Bovines/Cattle USP8 siRNA oligo Duplex | 538743 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
pGMoligo100055443 | Pre-made Equine/Horse USP8 siRNA oligo Duplex | 100055443 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
USP8 antibody/GMab
Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
---|
GM-Tg-hg-T83982-Ab | Human | Anti-Human USP8 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-rg-T83982-Ab | Rat | Anti-Rat USP8 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-mg-T83982-Ab | Mouse | Anti-Mouse USP8 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cynog-T83982-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque USP8 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-felg-T83982-Ab | Cat/Feline | Anti-Cat/Feline USP8 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-cang-T83982-Ab | Dog/Canine | Anti-Dog/Canine USP8 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-bovg-T83982-Ab | Bovines/Cattle | Anti-Bovines/Cattle USP8 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GM-Tg-equg-T83982-Ab | Equine/Horse | Anti-Equine/Horse USP8 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
USP8 recombinant protein
Cat No. | Species | Antigen Name | Expression Platform | Detail |
---|
GM-Tg-hg-T83982-Ag | Human | Human USP8 recombinant protein | Mammalian cell | Detail |
GM-Tg-rg-T83982-Ag | Rat | Rat USP8 recombinant protein | Mammalian cell | Detail |
GM-Tg-mg-T83982-Ag | Mouse | Mouse USP8 recombinant protein | Mammalian cell | Detail |
GM-Tg-cynog-T83982-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque USP8 recombinant protein | Mammalian cell | Detail |
GM-Tg-felg-T83982-Ag | Cat/Feline | Cat/Feline USP8 recombinant protein | Mammalian cell | Detail |
GM-Tg-cang-T83982-Ag | Dog/Canine | Dog/Canine USP8 recombinant protein | Mammalian cell | Detail |
GM-Tg-bovg-T83982-Ag | Bovines/Cattle | Bovines/Cattle USP8 recombinant protein | Mammalian cell | Detail |
GM-Tg-equg-T83982-Ag | Equine/Horse | Equine/Horse USP8 recombinant protein | Mammalian cell | Detail |