Recombinant multi-species CRYZ protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CRYZ protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008]
The Alternative Names of target: CRYZ,Cryz,NADPH:quinone reductase,Quinone oxidoreductase,Sez9,Zeta-crystallin
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T83284-Ag-1/ GM-Tg-hg-T83284-Ag-2 | Human CRYZ protein | Human |
| GM-Tg-rg-T83284-Ag-1/ GM-Tg-rg-T83284-Ag-2 | Rat CRYZ protein | Rat |
| GM-Tg-mg-T83284-Ag-1/ GM-Tg-mg-T83284-Ag-2 | Mouse CRYZ protein | Mouse |
| GM-Tg-cynog-T83284-Ag-1/ GM-Tg-cynog-T83284-Ag-2 | Cynomolgus/Rhesus macaque CRYZ protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T83284-Ag-1/ GM-Tg-felg-T83284-Ag-2 | Feline CRYZ protein | Feline |
| GM-Tg-cang-T83284-Ag-1/ GM-Tg-cang-T83284-Ag-2 | Canine CRYZ protein | Canine |
| GM-Tg-bovg-T83284-Ag-1/ GM-Tg-bovg-T83284-Ag-2 | Bovine CRYZ protein | Bovine |
| GM-Tg-equg-T83284-Ag-1/ GM-Tg-equg-T83284-Ag-2 | Equine CRYZ protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T83284-Ag-1/ GM-Tg-hg-T83284-Ag-2;
GM-Tg-rg-T83284-Ag-1/ GM-Tg-rg-T83284-Ag-2;
GM-Tg-mg-T83284-Ag-1/ GM-Tg-mg-T83284-Ag-2; GM-Tg-cynog-T83284-Ag-1/ GM-Tg-cynog-T83284-Ag-2; GM-Tg-felg-T83284-Ag-1/ GM-Tg-felg-T83284-Ag-2; GM-Tg-cang-T83284-Ag-1/ GM-Tg-cang-T83284-Ag-2; GM-Tg-bovg-T83284-Ag-1/ GM-Tg-bovg-T83284-Ag-2; GM-Tg-equg-T83284-Ag-1/ GM-Tg-equg-T83284-Ag-2 |
| Products Name | CRYZ protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CRYZ |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CRYZ protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.