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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008]
| Target ID |
GM-T83284
|
| Target Name |
CRYZ
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1429
|
| Gene ID |
100053415 (Equus caballus), 101086075 (Felis catus), 12972 (Mus musculus), 1429 (Homo sapiens) 281093 (Bos taurus), 362061 (Rattus norvegicus), 611431 (Canis lupus familiaris), 704403 (Macaca mulatta)
|
| Target Alternative Names |
CRYZ,Cryz,NADPH:quinone reductase,Quinone oxidoreductase,Sez9,Zeta-crystallin
|
| Uniprot Accession |
P47199,Q08257,O97764,Q6AYT0
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
Cancer
|
| Gene Ensembl |
ENSECAG00000008254, ENSMUSG00000028199, ENSG00000116791, ENSBTAG00000003162, ENSCAFG00845004617, ENSMMUG00000019493
|
CRYZ siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1429 | Pre-made Human CRYZ siRNA oligo Duplex | 1429 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362061 | Pre-made Rat Cryz siRNA oligo Duplex | 362061 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12972 | Pre-made Mouse Cryz/Sez9 siRNA oligo Duplex | 12972 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704403 | Pre-made Cynomolgus/Rhesus macaque CRYZ siRNA oligo Duplex | 704403 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086075 | Pre-made Cat/Feline CRYZ siRNA oligo Duplex | 101086075 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611431 | Pre-made Dog/Canine CRYZ siRNA oligo Duplex | 611431 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281093 | Pre-made Bovines/Cattle CRYZ siRNA oligo Duplex | 281093 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053415 | Pre-made Equine/Horse CRYZ siRNA oligo Duplex | 100053415 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CRYZ antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T83284-Ab | Human | Anti-Human CRYZ monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T83284-Ab | Rat | Anti-Rat CRYZ monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T83284-Ab | Mouse | Anti-Mouse CRYZ monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T83284-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CRYZ monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T83284-Ab | Cat/Feline | Anti-Cat/Feline CRYZ monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T83284-Ab | Dog/Canine | Anti-Dog/Canine CRYZ monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T83284-Ab | Bovines/Cattle | Anti-Bovines/Cattle CRYZ monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T83284-Ab | Equine/Horse | Anti-Equine/Horse CRYZ monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CRYZ recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T83284-Ag | Human | Human CRYZ recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T83284-Ag | Rat | Rat CRYZ recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T83284-Ag | Mouse | Mouse CRYZ recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T83284-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CRYZ recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T83284-Ag | Cat/Feline | Cat/Feline CRYZ recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T83284-Ag | Dog/Canine | Dog/Canine CRYZ recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T83284-Ag | Bovines/Cattle | Bovines/Cattle CRYZ recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T83284-Ag | Equine/Horse | Equine/Horse CRYZ recombinant protein | Mammalian cell | Detail |