Recombinant multi-species RPS6KA1/RSK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RPS6KA1/RSK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 90 kDa ribosomal protein S6 kinase 1 (p90-RSK 1,HU-1,MAP kinase-activated protein kinase 1a (MAPK-activated protein kinase 1a,MAPKAP kinase 1a,MAPKAPK-1a),MAPKAPK1,MAPKAPK1A,Mapkapk-1a,RPS6KA1,RSK,RSK1,Ribosomal S6 kinase 1 (RSK-1),Ribosomal protein S6 kinase alpha-1,Rps6ka1,Rsk,Rsk-1,Rsk1,S6K-alpha 1,S6K-alpha-1,p90-Rsk1,p90RSK1,p90Rsk,p90Rsk1,p90S6K,p90S6K),p90rsk
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T83202-Ag-1/ GM-Tg-hg-T83202-Ag-2 | Human RPS6KA1/RSK1 protein | Human |
| GM-Tg-rg-T83202-Ag-1/ GM-Tg-rg-T83202-Ag-2 | Rat RPS6KA1/RSK1 protein | Rat |
| GM-Tg-mg-T83202-Ag-1/ GM-Tg-mg-T83202-Ag-2 | Mouse RPS6KA1/RSK1 protein | Mouse |
| GM-Tg-cynog-T83202-Ag-1/ GM-Tg-cynog-T83202-Ag-2 | Cynomolgus/Rhesus macaque RPS6KA1/RSK1 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T83202-Ag-1/ GM-Tg-felg-T83202-Ag-2 | Feline RPS6KA1/RSK1 protein | Feline |
| GM-Tg-cang-T83202-Ag-1/ GM-Tg-cang-T83202-Ag-2 | Canine RPS6KA1/RSK1 protein | Canine |
| GM-Tg-bovg-T83202-Ag-1/ GM-Tg-bovg-T83202-Ag-2 | Bovine RPS6KA1/RSK1 protein | Bovine |
| GM-Tg-equg-T83202-Ag-1/ GM-Tg-equg-T83202-Ag-2 | Equine RPS6KA1/RSK1 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T83202-Ag-1/ GM-Tg-hg-T83202-Ag-2;
GM-Tg-rg-T83202-Ag-1/ GM-Tg-rg-T83202-Ag-2;
GM-Tg-mg-T83202-Ag-1/ GM-Tg-mg-T83202-Ag-2; GM-Tg-cynog-T83202-Ag-1/ GM-Tg-cynog-T83202-Ag-2; GM-Tg-felg-T83202-Ag-1/ GM-Tg-felg-T83202-Ag-2; GM-Tg-cang-T83202-Ag-1/ GM-Tg-cang-T83202-Ag-2; GM-Tg-bovg-T83202-Ag-1/ GM-Tg-bovg-T83202-Ag-2; GM-Tg-equg-T83202-Ag-1/ GM-Tg-equg-T83202-Ag-2 |
| Products Name | RPS6KA1/RSK1 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | RPS6KA1/RSK1 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine RPS6KA1/RSK1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
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pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.