Explore RPS6KA1/RSK1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T83202
|
| Target Name |
RPS6KA1/RSK1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6195
|
| Gene ID |
100057166 (Equus caballus), 101086492 (Felis catus), 20111 (Mus musculus), 487353 (Canis lupus familiaris)
533908 (Bos taurus), 6195 (Homo sapiens), 714794 (Macaca mulatta), 81771 (Rattus norvegicus)
|
| Target Alternative Names |
90 kDa ribosomal protein S6 kinase 1 (p90-RSK 1,HU-1,MAP kinase-activated protein kinase 1a (MAPK-activated protein kinase 1a,MAPKAP kinase 1a,MAPKAPK-1a),MAPKAPK1,MAPKAPK1A,Mapkapk-1a,RPS6KA1,RSK,RSK1,Ribosomal S6 kinase 1 (RSK-1),Ribosomal protein S6 kinase alpha-1,Rps6ka1,Rsk,Rsk-1,Rsk1,S6K-alpha 1,S6K-alpha-1,p90-Rsk1,p90RSK1,p90Rsk,p90Rsk1,p90S6K,p90S6K),p90rsk
|
| Uniprot Accession |
P18653,Q15418,Q63531
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
MAPK signaling pathway, Long-term potentiation, Neurotrophin signaling pathway, Insulin resistance, Yersinia infection, Chemical carcinogenesis - receptor activation
|
| Gene Ensembl |
ENSECAG00000016238, ENSMUSG00000003644, ENSCAFG00845011855, ENSBTAG00000014447, ENSG00000117676, ENSMMUG00000022111
|
| Target Classification |
Kinase
|
Pre-made viral vector of RPS6KA1/RSK1 cDNA Clones/ORF Plasmid
RPS6KA1/RSK1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6195 | Pre-made Human RPS6KA1/RSK/HU-1 siRNA oligo Duplex | 6195 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81771 | Pre-made Rat Rps6ka1/S6K-alpha 1 siRNA oligo Duplex | 81771 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20111 | Pre-made Mouse Rps6ka1/Rsk/Rsk1 siRNA oligo Duplex | 20111 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714794 | Pre-made Cynomolgus/Rhesus macaque RPS6KA1 siRNA oligo Duplex | 714794 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086492 | Pre-made Cat/Feline RPS6KA1 siRNA oligo Duplex | 101086492 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487353 | Pre-made Dog/Canine RPS6KA1 siRNA oligo Duplex | 487353 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo533908 | Pre-made Bovines/Cattle RPS6KA1 siRNA oligo Duplex | 533908 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100057166 | Pre-made Equine/Horse RPS6KA1 siRNA oligo Duplex | 100057166 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RPS6KA1/RSK1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T83202-Ab | Human | Anti-Human RPS6KA1/RSK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T83202-Ab | Rat | Anti-Rat RPS6KA1/RSK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T83202-Ab | Mouse | Anti-Mouse RPS6KA1/RSK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T83202-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RPS6KA1/RSK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T83202-Ab | Cat/Feline | Anti-Cat/Feline RPS6KA1/RSK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T83202-Ab | Dog/Canine | Anti-Dog/Canine RPS6KA1/RSK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T83202-Ab | Bovines/Cattle | Anti-Bovines/Cattle RPS6KA1/RSK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T83202-Ab | Equine/Horse | Anti-Equine/Horse RPS6KA1/RSK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
RPS6KA1/RSK1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T83202-Ag | Human | Human RPS6KA1/RSK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T83202-Ag | Rat | Rat RPS6KA1/RSK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T83202-Ag | Mouse | Mouse RPS6KA1/RSK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T83202-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RPS6KA1/RSK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T83202-Ag | Cat/Feline | Cat/Feline RPS6KA1/RSK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T83202-Ag | Dog/Canine | Dog/Canine RPS6KA1/RSK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T83202-Ag | Bovines/Cattle | Bovines/Cattle RPS6KA1/RSK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T83202-Ag | Equine/Horse | Equine/Horse RPS6KA1/RSK1 recombinant protein | Mammalian cell | Detail |
