Recombinant multi-species KEAP1 Cysteines protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KEAP1 Cysteines protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: Cytosolic inhibitor of Nrf2 (INrf2),INRF2,INrf2,Inrf2,KEAP1,KEAP1 Cysteines,KLHL19,Keap1,Kelch-like ECH-associated protein 1,Kelch-like protein 19,mKIAA0132

Target products collectionGo to KEAP1 Cysteines products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T83198-Ag-1/ GM-Tg-hg-T83198-Ag-2 Human KEAP1 Cysteines protein Human
GM-Tg-rg-T83198-Ag-1/ GM-Tg-rg-T83198-Ag-2 Rat KEAP1 Cysteines protein Rat
GM-Tg-mg-T83198-Ag-1/ GM-Tg-mg-T83198-Ag-2 Mouse KEAP1 Cysteines protein Mouse
GM-Tg-cynog-T83198-Ag-1/ GM-Tg-cynog-T83198-Ag-2 Cynomolgus/Rhesus macaque KEAP1 Cysteines protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T83198-Ag-1/ GM-Tg-felg-T83198-Ag-2 Feline KEAP1 Cysteines protein Feline
GM-Tg-cang-T83198-Ag-1/ GM-Tg-cang-T83198-Ag-2 Canine KEAP1 Cysteines protein Canine
GM-Tg-bovg-T83198-Ag-1/ GM-Tg-bovg-T83198-Ag-2 Bovine KEAP1 Cysteines protein Bovine
GM-Tg-equg-T83198-Ag-1/ GM-Tg-equg-T83198-Ag-2 Equine KEAP1 Cysteines protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T83198-Ag-1/ GM-Tg-hg-T83198-Ag-2; GM-Tg-rg-T83198-Ag-1/ GM-Tg-rg-T83198-Ag-2;
GM-Tg-mg-T83198-Ag-1/ GM-Tg-mg-T83198-Ag-2; GM-Tg-cynog-T83198-Ag-1/ GM-Tg-cynog-T83198-Ag-2;
GM-Tg-felg-T83198-Ag-1/ GM-Tg-felg-T83198-Ag-2; GM-Tg-cang-T83198-Ag-1/ GM-Tg-cang-T83198-Ag-2;
GM-Tg-bovg-T83198-Ag-1/ GM-Tg-bovg-T83198-Ag-2; GM-Tg-equg-T83198-Ag-1/ GM-Tg-equg-T83198-Ag-2
Products Name KEAP1 Cysteines protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name KEAP1 Cysteines
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KEAP1 Cysteines protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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