Explore KEAP1 Cysteines gene products and cross-species
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Target
sublocation: Introcelluar Protein.
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T83198
|
| Target Name |
KEAP1 Cysteines
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
9817
|
| Gene ID |
100055128 (Equus caballus), 101091260 (Felis catus), 117519 (Rattus norvegicus), 476713 (Canis lupus familiaris) 50868 (Mus musculus), 532791 (Bos taurus), 720514 (Macaca mulatta), 9817 (Homo sapiens)
|
| Target Alternative Names |
Cytosolic inhibitor of Nrf2 (INrf2),INRF2,INrf2,Inrf2,KEAP1,KEAP1 Cysteines,KLHL19,Keap1,Kelch-like ECH-associated protein 1,Kelch-like protein 19,mKIAA0132
|
| Uniprot Accession |
P57790,Q9Z2X8,Q14145
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Pathways in cancer, Hepatocellular carcinoma, Fluid shear stress and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000020533, ENSCAFG00845026598, ENSMUSG00000003308, ENSBTAG00000003543, ENSMMUG00000005218, ENSG00000079999
|
| Target Classification |
Pathway, Tumor-associated antigen (TAA)
|
Pre-made viral vector of KEAP1 Cysteines cDNA Clones/ORF Plasmid
KEAP1 Cysteines siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9817 | Pre-made Human KEAP1/INrf2/KLHL19 siRNA oligo Duplex | 9817 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo117519 | Pre-made Rat Keap1/Inrf2 siRNA oligo Duplex | 117519 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo50868 | Pre-made Mouse Keap1/INRF2/mKIAA0132 siRNA oligo Duplex | 50868 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo720514 | Pre-made Cynomolgus/Rhesus macaque KEAP1 siRNA oligo Duplex | 720514 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101091260 | Pre-made Cat/Feline KEAP1 siRNA oligo Duplex | 101091260 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476713 | Pre-made Dog/Canine KEAP1 siRNA oligo Duplex | 476713 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532791 | Pre-made Bovines/Cattle KEAP1 siRNA oligo Duplex | 532791 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055128 | Pre-made Equine/Horse KEAP1 siRNA oligo Duplex | 100055128 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KEAP1 Cysteines antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T83198-Ab | Human | Anti-Human KEAP1 Cysteines monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T83198-Ab | Rat | Anti-Rat KEAP1 Cysteines monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T83198-Ab | Mouse | Anti-Mouse KEAP1 Cysteines monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T83198-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KEAP1 Cysteines monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T83198-Ab | Cat/Feline | Anti-Cat/Feline KEAP1 Cysteines monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T83198-Ab | Dog/Canine | Anti-Dog/Canine KEAP1 Cysteines monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T83198-Ab | Bovines/Cattle | Anti-Bovines/Cattle KEAP1 Cysteines monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T83198-Ab | Equine/Horse | Anti-Equine/Horse KEAP1 Cysteines monoclonal antibody | mab | Therapeutics Target antibody | Detail |
KEAP1 Cysteines recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T83198-Ag | Human | Human KEAP1 Cysteines recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T83198-Ag | Rat | Rat KEAP1 Cysteines recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T83198-Ag | Mouse | Mouse KEAP1 Cysteines recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T83198-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KEAP1 Cysteines recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T83198-Ag | Cat/Feline | Cat/Feline KEAP1 Cysteines recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T83198-Ag | Dog/Canine | Dog/Canine KEAP1 Cysteines recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T83198-Ag | Bovines/Cattle | Bovines/Cattle KEAP1 Cysteines recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T83198-Ag | Equine/Horse | Equine/Horse KEAP1 Cysteines recombinant protein | Mammalian cell | Detail |