Recombinant multi-species CNTF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CNTF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010]
The Alternative Names of target: CNTF,Ciliary neurotrophic factor,Cntf,HCNTF

Target products collectionGo to CNTF products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T83192-Ag-1/ GM-Tg-hg-T83192-Ag-2 Human CNTF protein Human
GM-Tg-rg-T83192-Ag-1/ GM-Tg-rg-T83192-Ag-2 Rat CNTF protein Rat
GM-Tg-mg-T83192-Ag-1/ GM-Tg-mg-T83192-Ag-2 Mouse CNTF protein Mouse
GM-Tg-cynog-T83192-Ag-1/ GM-Tg-cynog-T83192-Ag-2 Cynomolgus/Rhesus macaque CNTF protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T83192-Ag-1/ GM-Tg-felg-T83192-Ag-2 Feline CNTF protein Feline
GM-Tg-cang-T83192-Ag-1/ GM-Tg-cang-T83192-Ag-2 Canine CNTF protein Canine
GM-Tg-bovg-T83192-Ag-1/ GM-Tg-bovg-T83192-Ag-2 Bovine CNTF protein Bovine
GM-Tg-equg-T83192-Ag-1/ GM-Tg-equg-T83192-Ag-2 Equine CNTF protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T83192-Ag-1/ GM-Tg-hg-T83192-Ag-2; GM-Tg-rg-T83192-Ag-1/ GM-Tg-rg-T83192-Ag-2;
GM-Tg-mg-T83192-Ag-1/ GM-Tg-mg-T83192-Ag-2; GM-Tg-cynog-T83192-Ag-1/ GM-Tg-cynog-T83192-Ag-2;
GM-Tg-felg-T83192-Ag-1/ GM-Tg-felg-T83192-Ag-2; GM-Tg-cang-T83192-Ag-1/ GM-Tg-cang-T83192-Ag-2;
GM-Tg-bovg-T83192-Ag-1/ GM-Tg-bovg-T83192-Ag-2; GM-Tg-equg-T83192-Ag-1/ GM-Tg-equg-T83192-Ag-2
Products Name CNTF protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CNTF
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CNTF protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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