Recombinant multi-species DNA-PKcs/PRKDC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DNA-PKcs/PRKDC protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]
The Alternative Names of target: DNA-PK,DNA-PK catalytic subunit,DNA-PKC,DNA-PKcs,DNA-dependent protein kinase catalytic subunit,DNAPDcs,DNAPK,DNAPKc,DNPK1,DOXNPH,HYRC,HYRC1,IMD26,PRKDC,Prkdc,Ser-473 kinase (S473K),XRCC7,dxnph,p350,p460,scid,slip
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T81735-Ag-1/ GM-Tg-hg-T81735-Ag-2 | Human DNA-PKcs/PRKDC protein | Human |
| GM-Tg-rg-T81735-Ag-1/ GM-Tg-rg-T81735-Ag-2 | Rat DNA-PKcs/PRKDC protein | Rat |
| GM-Tg-mg-T81735-Ag-1/ GM-Tg-mg-T81735-Ag-2 | Mouse DNA-PKcs/PRKDC protein | Mouse |
| GM-Tg-cynog-T81735-Ag-1/ GM-Tg-cynog-T81735-Ag-2 | Cynomolgus/Rhesus macaque DNA-PKcs/PRKDC protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T81735-Ag-1/ GM-Tg-felg-T81735-Ag-2 | Feline DNA-PKcs/PRKDC protein | Feline |
| GM-Tg-cang-T81735-Ag-1/ GM-Tg-cang-T81735-Ag-2 | Canine DNA-PKcs/PRKDC protein | Canine |
| GM-Tg-bovg-T81735-Ag-1/ GM-Tg-bovg-T81735-Ag-2 | Bovine DNA-PKcs/PRKDC protein | Bovine |
| GM-Tg-equg-T81735-Ag-1/ GM-Tg-equg-T81735-Ag-2 | Equine DNA-PKcs/PRKDC protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T81735-Ag-1/ GM-Tg-hg-T81735-Ag-2;
GM-Tg-rg-T81735-Ag-1/ GM-Tg-rg-T81735-Ag-2;
GM-Tg-mg-T81735-Ag-1/ GM-Tg-mg-T81735-Ag-2; GM-Tg-cynog-T81735-Ag-1/ GM-Tg-cynog-T81735-Ag-2; GM-Tg-felg-T81735-Ag-1/ GM-Tg-felg-T81735-Ag-2; GM-Tg-cang-T81735-Ag-1/ GM-Tg-cang-T81735-Ag-2; GM-Tg-bovg-T81735-Ag-1/ GM-Tg-bovg-T81735-Ag-2; GM-Tg-equg-T81735-Ag-1/ GM-Tg-equg-T81735-Ag-2 |
| Products Name | DNA-PKcs/PRKDC protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | DNA-PKcs/PRKDC |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DNA-PKcs/PRKDC protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
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entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.