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Target
sublocation: Introcelluar Protein.
This gene encodes the catalytic subunit of the DNA-dependent protein kinase (DNA-PK). It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination. The protein encoded is a member of the PI3/PI4-kinase family.[provided by RefSeq, Jul 2010]
| Target ID |
GM-T81735
|
| Target Name |
DNA-PKcs/PRKDC
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5591
|
| Gene ID |
101088389 (Felis catus), 19090 (Mus musculus), 360748 (Rattus norvegicus), 474176 (Canis lupus familiaris)
512740 (Bos taurus), 5591 (Homo sapiens), 708029 (Macaca mulatta), 791233 (Equus caballus)
|
| Target Alternative Names |
DNA-PK,DNA-PK catalytic subunit,DNA-PKC,DNA-PKcs,DNA-dependent protein kinase catalytic subunit,DNAPDcs,DNAPK,DNAPKc,DNPK1,DOXNPH,HYRC,HYRC1,IMD26,PRKDC,Prkdc,Ser-473 kinase (S473K),XRCC7,dxnph,p350,p460,scid,slip
|
| Uniprot Accession |
P97313,Q8WN22,P78527
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSMUSG00000022672, ENSCAFG00845027748, ENSBTAG00000017019, ENSG00000253729, ENSMMUG00000015347, ENSECAG00000020168
|
| Target Classification |
Kinase, Tumor-associated antigen (TAA)
|
DNA-PKcs/PRKDC siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5591 | Pre-made Human PRKDC/HYRC/p350 siRNA oligo Duplex | 5591 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360748 | Pre-made Rat Prkdc siRNA oligo Duplex | 360748 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19090 | Pre-made Mouse Prkdc/p460/scid siRNA oligo Duplex | 19090 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708029 | Pre-made Cynomolgus/Rhesus macaque PRKDC siRNA oligo Duplex | 708029 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101088389 | Pre-made Cat/Feline PRKDC siRNA oligo Duplex | 101088389 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474176 | Pre-made Dog/Canine PRKDC/DNA-PKcs siRNA oligo Duplex | 474176 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo512740 | Pre-made Bovines/Cattle PRKDC siRNA oligo Duplex | 512740 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo791233 | Pre-made Equine/Horse PRKDC/DNAPK/DNA-PK siRNA oligo Duplex | 791233 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DNA-PKcs/PRKDC antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T81735-Ab | Human | Anti-Human DNA-PKcs/PRKDC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T81735-Ab | Rat | Anti-Rat DNA-PKcs/PRKDC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T81735-Ab | Mouse | Anti-Mouse DNA-PKcs/PRKDC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T81735-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DNA-PKcs/PRKDC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T81735-Ab | Cat/Feline | Anti-Cat/Feline DNA-PKcs/PRKDC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T81735-Ab | Dog/Canine | Anti-Dog/Canine DNA-PKcs/PRKDC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T81735-Ab | Bovines/Cattle | Anti-Bovines/Cattle DNA-PKcs/PRKDC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T81735-Ab | Equine/Horse | Anti-Equine/Horse DNA-PKcs/PRKDC monoclonal antibody | mab | Therapeutics Target antibody | Detail |
DNA-PKcs/PRKDC recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T81735-Ag | Human | Human DNA-PKcs/PRKDC recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T81735-Ag | Rat | Rat DNA-PKcs/PRKDC recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T81735-Ag | Mouse | Mouse DNA-PKcs/PRKDC recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T81735-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DNA-PKcs/PRKDC recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T81735-Ag | Cat/Feline | Cat/Feline DNA-PKcs/PRKDC recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T81735-Ag | Dog/Canine | Dog/Canine DNA-PKcs/PRKDC recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T81735-Ag | Bovines/Cattle | Bovines/Cattle DNA-PKcs/PRKDC recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T81735-Ag | Equine/Horse | Equine/Horse DNA-PKcs/PRKDC recombinant protein | Mammalian cell | Detail |
