Recombinant multi-species PI3 Kinase p110 Alpha/PIK3CA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PI3 Kinase p110 Alpha/PIK3CA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22. [provided by RefSeq, Apr 2016]
The Alternative Names of target: 5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (PtdIns-3-kinase subunit p110-alpha,5-bisphosphate 3-kinase catalytic subunit alpha isoform,6330412C24Rik,CCM4,CLAPO,CLOVE,CWS5,HMH,MCAP,MCM,MCMTC,PI3 Kinase p110 Alpha,PI3-kinase subunit alpha,PI3K,PI3K-alpha,PI3Kalpha,PIK3CA,Phosphatidylinositol 4,Phosphoinositide 3-kinase alpha,Phosphoinositide-3-kinase catalytic alpha polypeptide,Pik3ca,PtdIns-3-kinase subunit alpha,Serine/threonine protein kinase PIK3CA,caPI3K,p110,p110-alpha,p110alpha,p110alpha)

Target products collectionGo to PI3 Kinase p110 Alpha/PIK3CA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T80276-Ag-1/ GM-Tg-hg-T80276-Ag-2 Human PI3 Kinase p110 Alpha/PIK3CA protein Human
GM-Tg-rg-T80276-Ag-1/ GM-Tg-rg-T80276-Ag-2 Rat PI3 Kinase p110 Alpha/PIK3CA protein Rat
GM-Tg-mg-T80276-Ag-1/ GM-Tg-mg-T80276-Ag-2 Mouse PI3 Kinase p110 Alpha/PIK3CA protein Mouse
GM-Tg-cynog-T80276-Ag-1/ GM-Tg-cynog-T80276-Ag-2 Cynomolgus/Rhesus macaque PI3 Kinase p110 Alpha/PIK3CA protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T80276-Ag-1/ GM-Tg-felg-T80276-Ag-2 Feline PI3 Kinase p110 Alpha/PIK3CA protein Feline
GM-Tg-cang-T80276-Ag-1/ GM-Tg-cang-T80276-Ag-2 Canine PI3 Kinase p110 Alpha/PIK3CA protein Canine
GM-Tg-bovg-T80276-Ag-1/ GM-Tg-bovg-T80276-Ag-2 Bovine PI3 Kinase p110 Alpha/PIK3CA protein Bovine
GM-Tg-equg-T80276-Ag-1/ GM-Tg-equg-T80276-Ag-2 Equine PI3 Kinase p110 Alpha/PIK3CA protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T80276-Ag-1/ GM-Tg-hg-T80276-Ag-2; GM-Tg-rg-T80276-Ag-1/ GM-Tg-rg-T80276-Ag-2;
GM-Tg-mg-T80276-Ag-1/ GM-Tg-mg-T80276-Ag-2; GM-Tg-cynog-T80276-Ag-1/ GM-Tg-cynog-T80276-Ag-2;
GM-Tg-felg-T80276-Ag-1/ GM-Tg-felg-T80276-Ag-2; GM-Tg-cang-T80276-Ag-1/ GM-Tg-cang-T80276-Ag-2;
GM-Tg-bovg-T80276-Ag-1/ GM-Tg-bovg-T80276-Ag-2; GM-Tg-equg-T80276-Ag-1/ GM-Tg-equg-T80276-Ag-2
Products Name PI3 Kinase p110 Alpha/PIK3CA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PI3 Kinase p110 Alpha/PIK3CA
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PI3 Kinase p110 Alpha/PIK3CA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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