Recombinant multi-species calreticulin/CALR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine calreticulin/CALR protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.[provided by RefSeq, May 2020]
The Alternative Names of target: CALR,CALR1,CRP55,CRT,Calr,Calregulin,Calreticulin,ERp60,Endoplasmic reticulum resident protein 60 (ERp60),HACBP,HEL-S-99n,RO,SSA,cC1qR,calreticulin,grp60

Target products collectionGo to calreticulin/CALR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T79821-Ag-1/ GM-Tg-hg-T79821-Ag-2 Human calreticulin/CALR protein Human
GM-Tg-rg-T79821-Ag-1/ GM-Tg-rg-T79821-Ag-2 Rat calreticulin/CALR protein Rat
GM-Tg-mg-T79821-Ag-1/ GM-Tg-mg-T79821-Ag-2 Mouse calreticulin/CALR protein Mouse
GM-Tg-cynog-T79821-Ag-1/ GM-Tg-cynog-T79821-Ag-2 Cynomolgus/Rhesus macaque calreticulin/CALR protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T79821-Ag-1/ GM-Tg-felg-T79821-Ag-2 Feline calreticulin/CALR protein Feline
GM-Tg-cang-T79821-Ag-1/ GM-Tg-cang-T79821-Ag-2 Canine calreticulin/CALR protein Canine
GM-Tg-bovg-T79821-Ag-1/ GM-Tg-bovg-T79821-Ag-2 Bovine calreticulin/CALR protein Bovine
GM-Tg-equg-T79821-Ag-1/ GM-Tg-equg-T79821-Ag-2 Equine calreticulin/CALR protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T79821-Ag-1/ GM-Tg-hg-T79821-Ag-2; GM-Tg-rg-T79821-Ag-1/ GM-Tg-rg-T79821-Ag-2;
GM-Tg-mg-T79821-Ag-1/ GM-Tg-mg-T79821-Ag-2; GM-Tg-cynog-T79821-Ag-1/ GM-Tg-cynog-T79821-Ag-2;
GM-Tg-felg-T79821-Ag-1/ GM-Tg-felg-T79821-Ag-2; GM-Tg-cang-T79821-Ag-1/ GM-Tg-cang-T79821-Ag-2;
GM-Tg-bovg-T79821-Ag-1/ GM-Tg-bovg-T79821-Ag-2; GM-Tg-equg-T79821-Ag-1/ GM-Tg-equg-T79821-Ag-2
Products Name calreticulin/CALR protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name calreticulin/CALR
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine calreticulin/CALR protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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