Recombinant multi-species THRA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine THRA protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 6430529J03Rik,AR7,CHNG6,EAR7,ERB-T-1,ERBA,ERBA1,Erba,NR1A1,NR1D1,Nr1a1,Nuclear receptor subfamily 1 group A member 1,Rvr,T3R[a],T3Ralpha,THRA,THRA1,THRA2,THRalpha,THRalpha1,THRalpha2,TRalpha,TRalpha1,TRalpha2,Thra,Thra1,Thra2,Thyroid hormone receptor alpha,V-erbA-related protein 7 (EAR-7),c-ERBA-1,c-erbA,c-erbA-1,c-erbA-alpha,c-erbAalpha

Target products collectionGo to THRA products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T79591-Ag-1/ GM-Tg-hg-T79591-Ag-2 Human THRA protein Human
GM-Tg-rg-T79591-Ag-1/ GM-Tg-rg-T79591-Ag-2 Rat THRA protein Rat
GM-Tg-mg-T79591-Ag-1/ GM-Tg-mg-T79591-Ag-2 Mouse THRA protein Mouse
GM-Tg-cynog-T79591-Ag-1/ GM-Tg-cynog-T79591-Ag-2 Cynomolgus/Rhesus macaque THRA protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T79591-Ag-1/ GM-Tg-felg-T79591-Ag-2 Feline THRA protein Feline
GM-Tg-cang-T79591-Ag-1/ GM-Tg-cang-T79591-Ag-2 Canine THRA protein Canine
GM-Tg-bovg-T79591-Ag-1/ GM-Tg-bovg-T79591-Ag-2 Bovine THRA protein Bovine
GM-Tg-equg-T79591-Ag-1/ GM-Tg-equg-T79591-Ag-2 Equine THRA protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T79591-Ag-1/ GM-Tg-hg-T79591-Ag-2; GM-Tg-rg-T79591-Ag-1/ GM-Tg-rg-T79591-Ag-2;
GM-Tg-mg-T79591-Ag-1/ GM-Tg-mg-T79591-Ag-2; GM-Tg-cynog-T79591-Ag-1/ GM-Tg-cynog-T79591-Ag-2;
GM-Tg-felg-T79591-Ag-1/ GM-Tg-felg-T79591-Ag-2; GM-Tg-cang-T79591-Ag-1/ GM-Tg-cang-T79591-Ag-2;
GM-Tg-bovg-T79591-Ag-1/ GM-Tg-bovg-T79591-Ag-2; GM-Tg-equg-T79591-Ag-1/ GM-Tg-equg-T79591-Ag-2
Products Name THRA protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name THRA
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine THRA protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.