Explore THRA gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
| Target ID |
GM-T79591
|
| Target Name |
THRA
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7067
|
| Gene ID |
100054511 (Equus caballus), 101095056 (Felis catus), 21833 (Mus musculus), 403601 (Canis lupus familiaris) 532621 (Bos taurus), 699650 (Macaca mulatta), 7067 (Homo sapiens), 81812 (Rattus norvegicus)
|
| Target Alternative Names |
6430529J03Rik,AR7,CHNG6,EAR7,ERB-T-1,ERBA,ERBA1,Erba,NR1A1,NR1D1,Nr1a1,Nuclear receptor subfamily 1 group A member 1,Rvr,T3R[a],T3Ralpha,THRA,THRA1,THRA2,THRalpha,THRalpha1,THRalpha2,TRalpha,TRalpha1,TRalpha2,Thra,Thra1,Thra2,Thyroid hormone receptor alpha,V-erbA-related protein 7 (EAR-7),c-ERBA-1,c-erbA,c-erbA-1,c-erbA-alpha,c-erbAalpha
|
| Uniprot Accession |
P63058,P10827,P63059
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Prostate Cancer
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway
|
| Gene Ensembl |
ENSMUSG00000058756, ENSBTAG00000010745, ENSMMUG00000002931, ENSG00000126351
|
| Target Classification |
Nuclear Receptors
|
Pre-made viral vector of THRA cDNA Clones/ORF Plasmid
THRA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7067 | Pre-made Human THRA/AR7/EAR7 siRNA oligo Duplex | 7067 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81812 | Pre-made Rat Thra/ERBA1/Thra1 siRNA oligo Duplex | 81812 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21833 | Pre-made Mouse Thra/Rvr/Erba siRNA oligo Duplex | 21833 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699650 | Pre-made Cynomolgus/Rhesus macaque THRA/NR1D1 siRNA oligo Duplex | 699650 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095056 | Pre-made Cat/Feline THRA siRNA oligo Duplex | 101095056 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403601 | Pre-made Dog/Canine THRA siRNA oligo Duplex | 403601 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo532621 | Pre-made Bovines/Cattle THRA siRNA oligo Duplex | 532621 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054511 | Pre-made Equine/Horse THRA siRNA oligo Duplex | 100054511 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
THRA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T79591-Ab | Human | Anti-Human THRA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T79591-Ab | Rat | Anti-Rat THRA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T79591-Ab | Mouse | Anti-Mouse THRA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T79591-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque THRA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T79591-Ab | Cat/Feline | Anti-Cat/Feline THRA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T79591-Ab | Dog/Canine | Anti-Dog/Canine THRA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T79591-Ab | Bovines/Cattle | Anti-Bovines/Cattle THRA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T79591-Ab | Equine/Horse | Anti-Equine/Horse THRA monoclonal antibody | mab | Therapeutics Target antibody | Detail |
THRA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T79591-Ag | Human | Human THRA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T79591-Ag | Rat | Rat THRA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T79591-Ag | Mouse | Mouse THRA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T79591-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque THRA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T79591-Ag | Cat/Feline | Cat/Feline THRA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T79591-Ag | Dog/Canine | Dog/Canine THRA recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T79591-Ag | Bovines/Cattle | Bovines/Cattle THRA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T79591-Ag | Equine/Horse | Equine/Horse THRA recombinant protein | Mammalian cell | Detail |