Recombinant multi-species IL-5/IL5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-5/IL5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
The Alternative Names of target: B-cell differentiation factor I,EDF,Eosinophil differentiation factor,IL-5,IL5,Il-5,Il5,Interleukin-5,T-cell replacing factor (TRF),TRF

Target products collectionGo to IL-5/IL5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T78585-Ag-1/ GM-Tg-hg-T78585-Ag-2 Human IL-5/IL5 protein Human
GM-Tg-rg-T78585-Ag-1/ GM-Tg-rg-T78585-Ag-2 Rat IL-5/IL5 protein Rat
GM-Tg-mg-T78585-Ag-1/ GM-Tg-mg-T78585-Ag-2 Mouse IL-5/IL5 protein Mouse
GM-Tg-cynog-T78585-Ag-1/ GM-Tg-cynog-T78585-Ag-2 Cynomolgus/Rhesus macaque IL-5/IL5 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T78585-Ag-1/ GM-Tg-felg-T78585-Ag-2 Feline IL-5/IL5 protein Feline
GM-Tg-cang-T78585-Ag-1/ GM-Tg-cang-T78585-Ag-2 Canine IL-5/IL5 protein Canine
GM-Tg-bovg-T78585-Ag-1/ GM-Tg-bovg-T78585-Ag-2 Bovine IL-5/IL5 protein Bovine
GM-Tg-equg-T78585-Ag-1/ GM-Tg-equg-T78585-Ag-2 Equine IL-5/IL5 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T78585-Ag-1/ GM-Tg-hg-T78585-Ag-2; GM-Tg-rg-T78585-Ag-1/ GM-Tg-rg-T78585-Ag-2;
GM-Tg-mg-T78585-Ag-1/ GM-Tg-mg-T78585-Ag-2; GM-Tg-cynog-T78585-Ag-1/ GM-Tg-cynog-T78585-Ag-2;
GM-Tg-felg-T78585-Ag-1/ GM-Tg-felg-T78585-Ag-2; GM-Tg-cang-T78585-Ag-1/ GM-Tg-cang-T78585-Ag-2;
GM-Tg-bovg-T78585-Ag-1/ GM-Tg-bovg-T78585-Ag-2; GM-Tg-equg-T78585-Ag-1/ GM-Tg-equg-T78585-Ag-2
Products Name IL-5/IL5 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name IL-5/IL5
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine IL-5/IL5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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