Recombinant multi-species LOX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LOX protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections. [provided by RefSeq, Jul 2016]
The Alternative Names of target: AAT10,H-rev142,LOX,Lox,Lysyl oxidase,Protein-lysine 6-oxidase,Rrg1,TSC-160,rrg

Target products collectionGo to LOX products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T75152-Ag-1/ GM-Tg-hg-T75152-Ag-2 Human LOX protein Human
GM-Tg-rg-T75152-Ag-1/ GM-Tg-rg-T75152-Ag-2 Rat LOX protein Rat
GM-Tg-mg-T75152-Ag-1/ GM-Tg-mg-T75152-Ag-2 Mouse LOX protein Mouse
GM-Tg-cynog-T75152-Ag-1/ GM-Tg-cynog-T75152-Ag-2 Cynomolgus/Rhesus macaque LOX protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T75152-Ag-1/ GM-Tg-felg-T75152-Ag-2 Feline LOX protein Feline
GM-Tg-cang-T75152-Ag-1/ GM-Tg-cang-T75152-Ag-2 Canine LOX protein Canine
GM-Tg-bovg-T75152-Ag-1/ GM-Tg-bovg-T75152-Ag-2 Bovine LOX protein Bovine
GM-Tg-equg-T75152-Ag-1/ GM-Tg-equg-T75152-Ag-2 Equine LOX protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T75152-Ag-1/ GM-Tg-hg-T75152-Ag-2; GM-Tg-rg-T75152-Ag-1/ GM-Tg-rg-T75152-Ag-2;
GM-Tg-mg-T75152-Ag-1/ GM-Tg-mg-T75152-Ag-2; GM-Tg-cynog-T75152-Ag-1/ GM-Tg-cynog-T75152-Ag-2;
GM-Tg-felg-T75152-Ag-1/ GM-Tg-felg-T75152-Ag-2; GM-Tg-cang-T75152-Ag-1/ GM-Tg-cang-T75152-Ag-2;
GM-Tg-bovg-T75152-Ag-1/ GM-Tg-bovg-T75152-Ag-2; GM-Tg-equg-T75152-Ag-1/ GM-Tg-equg-T75152-Ag-2
Products Name LOX protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name LOX
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LOX protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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