Explore LOX gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections. [provided by RefSeq, Jul 2016]
| Target ID |
GM-T75152
|
| Target Name |
LOX
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4015
|
| Gene ID |
100064016 (Equus caballus), 101092985 (Felis catus), 16948 (Mus musculus), 24914 (Rattus norvegicus)
280841 (Bos taurus), 4015 (Homo sapiens), 481478 (Canis lupus familiaris), 699997 (Macaca mulatta)
|
| Target Alternative Names |
AAT10,H-rev142,LOX,Lox,Lysyl oxidase,Protein-lysine 6-oxidase,Rrg1,TSC-160,rrg
|
| Uniprot Accession |
P28301,P16636,P33072,P28300
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000014771, ENSMUSG00000024529, ENSBTAG00000012994, ENSG00000113083, ENSCAFG00845007914, ENSMMUG00000056626
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of LOX cDNA Clones/ORF Plasmid
LOX siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4015 | Pre-made Human LOX/AAT10 siRNA oligo Duplex | 4015 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24914 | Pre-made Rat Lox/Rrg1/H-rev142 siRNA oligo Duplex | 24914 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16948 | Pre-made Mouse Lox/rrg/TSC-160 siRNA oligo Duplex | 16948 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699997 | Pre-made Cynomolgus/Rhesus macaque LOX siRNA oligo Duplex | 699997 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092985 | Pre-made Cat/Feline LOX siRNA oligo Duplex | 101092985 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481478 | Pre-made Dog/Canine LOX siRNA oligo Duplex | 481478 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280841 | Pre-made Bovines/Cattle LOX siRNA oligo Duplex | 280841 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064016 | Pre-made Equine/Horse LOX siRNA oligo Duplex | 100064016 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LOX antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T75152-Ab | Human | Anti-Human LOX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T75152-Ab | Rat | Anti-Rat LOX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T75152-Ab | Mouse | Anti-Mouse LOX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T75152-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LOX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T75152-Ab | Cat/Feline | Anti-Cat/Feline LOX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T75152-Ab | Dog/Canine | Anti-Dog/Canine LOX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T75152-Ab | Bovines/Cattle | Anti-Bovines/Cattle LOX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T75152-Ab | Equine/Horse | Anti-Equine/Horse LOX monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
LOX recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T75152-Ag | Human | Human LOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T75152-Ag | Rat | Rat LOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T75152-Ag | Mouse | Mouse LOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T75152-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T75152-Ag | Cat/Feline | Cat/Feline LOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T75152-Ag | Dog/Canine | Dog/Canine LOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T75152-Ag | Bovines/Cattle | Bovines/Cattle LOX recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T75152-Ag | Equine/Horse | Equine/Horse LOX recombinant protein | Mammalian cell | Detail |
