Recombinant multi-species KDM4C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KDM4C protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
The Alternative Names of target: 2410141F18Rik,GASC1,Gasc1,Gene amplified in squamous cell carcinoma 1 protein (GASC-1 protein),JHDM3C,JMJD2C,JmjC domain-containing histone demethylation protein 3C,Jmjd2c,Jumonji domain-containing protein 2C,KDM4C,Kdm4c,Lysine-specific demethylase 4C,TDRD14C,[histone H3]-trimethyl-L-lysine(9) demethylase 4C
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T73863-Ag-1/ GM-Tg-hg-T73863-Ag-2 | Human KDM4C protein | Human |
| GM-Tg-rg-T73863-Ag-1/ GM-Tg-rg-T73863-Ag-2 | Rat KDM4C protein | Rat |
| GM-Tg-mg-T73863-Ag-1/ GM-Tg-mg-T73863-Ag-2 | Mouse KDM4C protein | Mouse |
| GM-Tg-cynog-T73863-Ag-1/ GM-Tg-cynog-T73863-Ag-2 | Cynomolgus/Rhesus macaque KDM4C protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T73863-Ag-1/ GM-Tg-felg-T73863-Ag-2 | Feline KDM4C protein | Feline |
| GM-Tg-cang-T73863-Ag-1/ GM-Tg-cang-T73863-Ag-2 | Canine KDM4C protein | Canine |
| GM-Tg-bovg-T73863-Ag-1/ GM-Tg-bovg-T73863-Ag-2 | Bovine KDM4C protein | Bovine |
| GM-Tg-equg-T73863-Ag-1/ GM-Tg-equg-T73863-Ag-2 | Equine KDM4C protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T73863-Ag-1/ GM-Tg-hg-T73863-Ag-2;
GM-Tg-rg-T73863-Ag-1/ GM-Tg-rg-T73863-Ag-2;
GM-Tg-mg-T73863-Ag-1/ GM-Tg-mg-T73863-Ag-2; GM-Tg-cynog-T73863-Ag-1/ GM-Tg-cynog-T73863-Ag-2; GM-Tg-felg-T73863-Ag-1/ GM-Tg-felg-T73863-Ag-2; GM-Tg-cang-T73863-Ag-1/ GM-Tg-cang-T73863-Ag-2; GM-Tg-bovg-T73863-Ag-1/ GM-Tg-bovg-T73863-Ag-2; GM-Tg-equg-T73863-Ag-1/ GM-Tg-equg-T73863-Ag-2 |
| Products Name | KDM4C protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | KDM4C |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KDM4C protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
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characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.