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Target
sublocation: Introcelluar Protein.
This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
| Target ID |
GM-T73863
|
| Target Name |
KDM4C
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
23081
|
| Gene ID |
100060699 (Equus caballus), 101100423 (Felis catus), 23081 (Homo sapiens), 298144 (Rattus norvegicus) 474704 (Canis lupus familiaris), 535671 (Bos taurus), 715273 (Macaca mulatta), 76804 (Mus musculus)
|
| Target Alternative Names |
2410141F18Rik,GASC1,Gasc1,Gene amplified in squamous cell carcinoma 1 protein (GASC-1 protein),JHDM3C,JMJD2C,JmjC domain-containing histone demethylation protein 3C,Jmjd2c,Jumonji domain-containing protein 2C,KDM4C,Kdm4c,Lysine-specific demethylase 4C,TDRD14C,[histone H3]-trimethyl-L-lysine(9) demethylase 4C
|
| Uniprot Accession |
Q9H3R0,Q8VCD7
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000024063, ENSG00000107077, ENSCAFG00845025468, ENSBTAG00000043987, ENSMMUG00000015985, ENSMUSG00000028397
|
| Target Classification |
Epigenetic
|
Pre-made viral vector of KDM4C cDNA Clones/ORF Plasmid
KDM4C siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo23081 | Pre-made Human KDM4C/GASC1/JHDM3C siRNA oligo Duplex | 23081 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo298144 | Pre-made Rat Kdm4c/Jmjd2c siRNA oligo Duplex | 298144 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo76804 | Pre-made Mouse Kdm4c/Gasc1/Jmjd2c siRNA oligo Duplex | 76804 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715273 | Pre-made Cynomolgus/Rhesus macaque KDM4C siRNA oligo Duplex | 715273 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101100423 | Pre-made Cat/Feline KDM4C siRNA oligo Duplex | 101100423 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474704 | Pre-made Dog/Canine KDM4C/JMJD2C siRNA oligo Duplex | 474704 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo535671 | Pre-made Bovines/Cattle KDM4C siRNA oligo Duplex | 535671 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060699 | Pre-made Equine/Horse KDM4C/JMJD2C siRNA oligo Duplex | 100060699 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KDM4C antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T73863-Ab | Human | Anti-Human KDM4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T73863-Ab | Rat | Anti-Rat KDM4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T73863-Ab | Mouse | Anti-Mouse KDM4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T73863-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KDM4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T73863-Ab | Cat/Feline | Anti-Cat/Feline KDM4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T73863-Ab | Dog/Canine | Anti-Dog/Canine KDM4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T73863-Ab | Bovines/Cattle | Anti-Bovines/Cattle KDM4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T73863-Ab | Equine/Horse | Anti-Equine/Horse KDM4C monoclonal antibody | mab | Therapeutics Target antibody | Detail |
KDM4C recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T73863-Ag | Human | Human KDM4C recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T73863-Ag | Rat | Rat KDM4C recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T73863-Ag | Mouse | Mouse KDM4C recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T73863-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KDM4C recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T73863-Ag | Cat/Feline | Cat/Feline KDM4C recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T73863-Ag | Dog/Canine | Dog/Canine KDM4C recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T73863-Ag | Bovines/Cattle | Bovines/Cattle KDM4C recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T73863-Ag | Equine/Horse | Equine/Horse KDM4C recombinant protein | Mammalian cell | Detail |