Recombinant multi-species CLK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
The Alternative Names of target: CDC-like kinase 2,CLK2,Clk2,Dual specificity protein kinase CLK2

Target products collectionGo to CLK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T73725-Ag-1/ GM-Tg-hg-T73725-Ag-2 Human CLK2 protein Human
GM-Tg-rg-T73725-Ag-1/ GM-Tg-rg-T73725-Ag-2 Rat CLK2 protein Rat
GM-Tg-mg-T73725-Ag-1/ GM-Tg-mg-T73725-Ag-2 Mouse CLK2 protein Mouse
GM-Tg-cynog-T73725-Ag-1/ GM-Tg-cynog-T73725-Ag-2 Cynomolgus/Rhesus macaque CLK2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T73725-Ag-1/ GM-Tg-felg-T73725-Ag-2 Feline CLK2 protein Feline
GM-Tg-cang-T73725-Ag-1/ GM-Tg-cang-T73725-Ag-2 Canine CLK2 protein Canine
GM-Tg-bovg-T73725-Ag-1/ GM-Tg-bovg-T73725-Ag-2 Bovine CLK2 protein Bovine
GM-Tg-equg-T73725-Ag-1/ GM-Tg-equg-T73725-Ag-2 Equine CLK2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T73725-Ag-1/ GM-Tg-hg-T73725-Ag-2; GM-Tg-rg-T73725-Ag-1/ GM-Tg-rg-T73725-Ag-2;
GM-Tg-mg-T73725-Ag-1/ GM-Tg-mg-T73725-Ag-2; GM-Tg-cynog-T73725-Ag-1/ GM-Tg-cynog-T73725-Ag-2;
GM-Tg-felg-T73725-Ag-1/ GM-Tg-felg-T73725-Ag-2; GM-Tg-cang-T73725-Ag-1/ GM-Tg-cang-T73725-Ag-2;
GM-Tg-bovg-T73725-Ag-1/ GM-Tg-bovg-T73725-Ag-2; GM-Tg-equg-T73725-Ag-1/ GM-Tg-equg-T73725-Ag-2
Products Name CLK2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CLK2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CLK2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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